JN1023型重组人泛素结合酶E2-L6(UBCEL6)厂家

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JN1023型重组人泛素结合酶E2-L6(UBCEL6)厂家直销由专业试剂供应商北京百奥莱博提供，用于生化研究，本产品质量好，且极具价格优势，深为用户称道，了解更多重组人泛素结合酶E2-L6(UBCEL6)等分子生物学试剂产品请联系我司咨询订购。

名称：JN1023型重组人泛素结合酶E2-L6(UBCEL6)厂家直销
英文名：Recombinant Human Ubiquitin-Conjugating Enzyme E2 L6
编号：JN1023
品牌：百奥莱博
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Ser153在C端含有His标签。

UBE2L6质量控制：＞95%(还原性SDS-PAGE)

UBE2L6制剂：液体

UBE2L6保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于UBE2L6：
Ubiquitin/ISG15-Conjugating Enzyme E2 L6 (UBE2L6) is an enzyme member of the E2 ubiquitin-conjugating enzyme family. UBE2L6 plays a same function as UBE2D, it catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. UBE2L6 promotes ubiquitination and subsequent proteasomal degradation of FLT3. It has functions in the E6/E6-AP-induced ubiquitination of p53/TP53.

关于JN1023型重组人泛素结合酶E2-L6(UBCEL6)厂家直销的更详细说明，请致电我公司咨询，我们将以最饱满的热情为您提供解答，此外，我公司专业供应下列产品：

·重组人肿瘤坏死因子α(N端His标签)
编号：JN0468
英文名称：Recombinant Human Tumor Necrosis Factor alpha
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Gly57-Leu233在N端含有His标签。

TNF-alpha质量控制：＞95%(还原性SDS-PAGE)

TNF-alpha制剂：冻干品

TNF-alpha保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNF-alpha复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNF-alpha：
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete little or no TNF-α. Synthesis of TNF-α can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumor activity of TNF-α has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF-α mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF-α that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumor activity and reduced systemic toxicity in mice comp*(代"a")red with murine TNF-α, which binds to both murine TNF receptors. Based on these results, many TNF-α mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumor cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF-α High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.


JN1023型重组人泛素结合酶E2-L6(UBCEL6)厂家直销关键词：JN1023,重组人泛素结合酶E2-L6蛋白,重组泛素结合酶E2-L6,重组人UBCEL6


·重组人小白蛋白α(PVALB)
编号：JN1948
英文名称：Recombinant Human Parvalbumin alpha
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Ser2-Ser110在C端含有His标签。

PVALB质量控制：＞95%(还原性SDS-PAGE)

PVALB制剂：冻干品

PVALB保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

PVALB复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于PVALB：
Parvalbumin α (PVALB) is a member of the parvalbumin family. PVALB is a high affinity calcium ion-binding protein, with two EF hand domains. PVALB is structurally and functionally similar to calmodulin and troponin C, it can bind two calcium ions. Parvalbumin is thought to be involved in relaxation after contraction in muscle. Parvalbumin is expressed in a specific population of GABAergic interneurons, which are believed to have a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus.


JN1023型重组人泛素结合酶E2-L6(UBCEL6)厂家直销关键词：JN1023,重组人泛素结合酶E2-L6蛋白,重组泛素结合酶E2-L6,重组人UBCEL6


·重组人Importinβ1(KPNB1)(核转运受体蛋白)(输入蛋白β1)
编号：JN1588
英文名称：Recombinant Human Importin Subunit Beta-1
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Ala876在N端含有His标签。

KPNB1质量控制：＞95%(还原性SDS-PAGE)

KPNB1制剂：液体

KPNB1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于KPNB1：
Importin subunit beta-1(KPNB1) is a member of the importin beta family. KPNB1 contains 1 importin N-terminal domain and 19 HEAT repeats. It is involved in nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. Its functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor. The import of proteins containing a classical nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits. Each of these subunits is part of the karyopherin family of proteins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta do*(代"c")ks the complex at the cytoplasmic side of the nuclear pore complex. It mediates autonomously the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5.

我公司生产供应销*(代"售")的分子生物学试剂正全品类优惠促销，十分期待您的咨询选购JN1023型重组人泛素结合酶E2-L6(UBCEL6)厂家直销。