重组人骨形成蛋白受体II(BMPR-II) 分子生物学试剂

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

重组人骨形成蛋白受体II(BMPR-II) 分子生物学试剂的品牌：百奥莱博，是优质的分子生物学试剂产品，用于科研实验，本产品质量好，且极具价格优势，深为用户称道，了解更多重组人骨形成蛋白受体II(BMPR-II)等分子生物学试剂产品请联系我司咨询订购。

名称：重组人骨形成蛋白受体II(BMPR-II) 分子生物学试剂
英文名：Recombinant Human Bone Morphogenetic Protein Receptor Type IIA
产地：国产|进口
编号：JN0513
品牌：百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser27-Ile151在C端含有His标签。

BMPR-II质量控制：＞95%(还原性SDS-PAGE)

BMPR-II制剂：冻干品

BMPR-II保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

BMPR-II复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于BMPR-II：
Bone Morphogenetic Protein Receptor II (BMPR-II) is a Type II Serine/Threonine Kinase that mediates cellular responses to BMPs. BMPR-II is characterized by lacking of a GS domain, and presence of a C-terminal extension typical of type II receptors. BMPRII binds BMP2, BMP4 and BMP7 weakly in the absence of type I receptor, and the binding can be facilitated by the presence of the type I receptor, including BMPR-IA/Brk1, BMPR-IB, and ActR-I. BMPR-II plays a key role in cell growth. Defects in BMPR-II have been linked to primary pulmonary hypertension. Human and mouse BMPR-II are highly conserved and share 97 % amino acid sequence identity.

更多有关重组人骨形成蛋白受体II(BMPR-II) 分子生物学试剂的价格及使用说明等，请联系我们的业务经理王欣女士咨询，我公司还销*(代"售")以下产品：

·重组小鼠溶酶体整合膜蛋白(LIMPII)(SR-B2)
编号：JN1550
英文名称：Recombinant Mouse Lysosomal Integral Membrane Protein II
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg27-Thr432在C端含有His标签。

LIMPII/SR-B2 质量控制：＞95%(还原性SDS-PAGE)

LIMPII/SR-B2 制剂：冻干品

LIMPII/SR-B2 保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

LIMPII/SR-B2 复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于LIMPII/SR-B2 ：
Lysosome membrane protein II (LIMPII)，also known as SCARB2, is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal comp*(代"a")rtment. The protein deficiency in mice was reported to imp*(代"a")ir cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. In addition, LIMPII also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation.


重组人骨形成蛋白受体II(BMPR-II) 分子生物学试剂关键词：重组人BMPR-II,JN0513,重组骨形成蛋白受体II,重组人骨形成蛋白受体II,重组人骨形成蛋白受体II蛋白


·精*酸甲基转移酶2
编号：JN0082
英文名称：PRMT2
规格：10μg
  精*酸甲基转移酶可以甲基化蛋白质精*酸残基上的胍基氮，靶蛋白包括STAT3, FBL, 组蛋白H4等。

催化反应：
2 S-adenosyl-L-methionine + [protein]-L-arginine = 2 S-adenosyl-L-hom℃ysteine + [protein]-N(omega),N(omega)-dimethyl-L-arginine。

动力学常数：
KM=2.6 µM for AdoMet
KM=3.3 µM for H4
Vmax=1.4 nmol/min/mg enzyme toward AdoMet
Vmax=1.5 nmol/min/mg enzyme toward H4

·重组人神经生长因子受体相关蛋白1(NGFRAP1)(BEX3)
编号：JN1091
英文名称：Recombinant Human Nerve Growth Factor Receptor Associated Protein 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met1-Pro111在C端带有Fc标签。

NGFRAP1/BEX3质量控制：＞95%(还原性SDS-PAGE)

NGFRAP1/BEX3制剂：冻干品

NGFRAP1/BEX3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

NGFRAP1/BEX3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于NGFRAP1/BEX3：
NGFRAP1, also called BEX3, can encode protein BEX3. BEX3 shuttles between the cytoplasm and the nucleus, and it associates with replicating mitochondria. BEX3 interacts with 14-3-3 epsilon(YWHAE) or DIABLO/SMAC to function as a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Many disease, such as neuronal death and neurogenetic diseases, is closely related to the BEX3.


重组人骨形成蛋白受体II(BMPR-II) 分子生物学试剂关键词：重组人BMPR-II,JN0513,重组骨形成蛋白受体II,重组人骨形成蛋白受体II,重组人骨形成蛋白受体II蛋白

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