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文献和实验Selecting Patients for KIT Inhibition in Melanoma
within an individual tumor, define clinically relevant genetic subgroups of disease, and permit improved patient selection for targeted therapies. Melanomas harboring genetic alterations of KIT have been demonstrated to constitute one such molecular subgroup
Targeted Exon Sequencing by In‐Solution Hybrid Selection
a protocol for the targeted enrichment of exons from randomly sheared genomic DNA libraries using an in?solution hybrid selection approach for sequencing on an Illumina Genome Analyzer II. The steps for designing and ordering a hybrid selection oligo pool
•Positive selection resulting in low background Zero Blunt® TOPO® PCR Cloning Kit for Sequencing •≥95% recombinants K2875-20 •Positive selection resulting in low
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