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文献和实验one of the most dynamic areas of innovation in high-throughput screening (HTS). The driver of this innovation is the demand for more leads from more complex targets. Genomics discovery efforts have generated many potential targets for HTS, but the biochemical nature
The Interweaving of Cheminformatics and HTS
libraries and the analysis of HTS results, to the discovery of functional relationships between compounds and their targets.
Application of Fluorescence Polarization in HTS Assays
Steady-state measurements of fluorescence polarization have been widely adopted in the field of high-throughput screening for the study of biomolecular interactions. This chapter reviews the basic theory of fluorescence polarization
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