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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Peptide with sequence C-RSLVKPENYRRLD, from the internal region of the protein sequence according to NP_000542.1; NP_937799.1.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse, Rat
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX89268
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Goat
- 应用范围:
WB, IHC-P, ELISA, Sandwich ELISA
- 浓度:
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
This antibody is expected to recognise both reported isoforms (NP_000542.1 and NP_937799.1).
- 抗体英文名:
Von Hippel Lindau antibody, Internal
- 抗体名:
Von Hippel Lindau 抗体, Internal
- 规格:
100 μg
ELISA analysis of Von Hippel Lindau protein using GTX89268 Von Hippel Lindau antibody, Internal.
Capture : GTX101087 (2.5μg/ml)
Detection : GTX89268 (1.5μg/ml)
IHC-P analysis of human kidney using GTX89268 Von Hippel Lindau antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 5μg/ml
WB analysis of human ovary lysate using GTX89268 Von Hippel Lindau antibody, Internal.
Dilution : 0.01μg/ml
Loading : 35μg protein in RIPA buffer
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文献和实验Molecular Analysis of the von Hippel-Lindau Disease Gene
Von Hippel-Lindau (VHL) disease is an autosomal dominant disorder that predisposes the affected individual to develop characteristic tumors. These include CNS hemangioblastoma, retinal angiomas, endolymphatic sac tumors, pancreatic cysts
Polymerase Chain Reaction Detection of DNA Sequence Deletions
to disable tumor suppression (1 ). As might be expected, the effect of “two hits” on tumor-suppressor gene integrity—e.g., deletion of one allele and mutation of the remaining allele—would disable the gene from encoding gene product. The von Hippel-Lindau
Transcriptional Regulation of Genes via Hypoxia-Inducible Factor
Hypoxia-inducible factor (HIF) is the principal transcription factor that regulates adaptive physiologic responses to compromised oxygen tension. von Hippel–Lindau (VHL) tumor-suppressor protein binds and ubiquitylates the catalytic α subunit
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