万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
2-8℃
- 保质期:
见包装
- 英文名:
Jatrorrhizine
- 库存:
大量现货
- 供应商:
上海研谨生物
- CAS号:
3621-38-3
- 规格:
10mg
药根碱
分析标准品,HPLC≥98%
Jatrorrhizine
CAS号:3621-38-3
分子式:C20H20NO4
分子量:338.382
MDL:MFCD01310242
|
货号 |
规格/参数/品牌 |
价格 |
货期 |
|
YJ-B21476-10mg |
分析标准品,HPLC≥98% |
¥420.00 |
现货 |
|
YJ-B21476-20mg |
分析标准品,HPLC≥98% |
¥560.00 |
现货 |
产品介绍
熔点:208-210℃
外观:红黄色针状结晶
溶解性:溶于水和乙醇
储存条件:2-8℃
注意:部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验参考文献(53篇)
53. [IF=4.1] Yufeng Huang et al."Study on the correlation between alkaloids and tastes of Coptis Rhizome from four species based on UHPLC-QQQ-MS/MS combined with electronic tongue technique."Frontiers in Plant Science.2024 Nov;15:
52. [IF=3.8] Nie Wenlong et al."Exploring the influence of polysaccharide on gastrointestinal stability, drug release and formation mechanism of nanoparticles in Zhimu and Huangbai herb pair decoction."Scientific Reports.2025 Mar;15(1):1-16
51. [IF=3.1] Xinyi Jiao et al."A multi-level strategy based on comprehensive two-dimensional liquid chromatography-Q-Orbitrap-mass spectrometry combined with PLS regression model and RT-Ensemble Pred model to intelligently distinguish different geographical locations
50. [IF=2.8] Jingbo Yu et al."Non-target metabolomics unravels the effect and mechanism of Lianpu Drink on spleen-stomach damp-heat syndrome."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES.2024 Oct;1246:124281
49. [IF=2.5] Li Chen et al."Optimization of Extraction Process of Total Alkaloids from Thalictrum delavayi Franch. and Their Therapeutic Potential on Pulmonary Infection Caused by Klebsiella pneumoniae and Escherichia coli."Separations.2024 Jul;11(7):210
48. [IF=3] Haiwen Zhang et al."Alkaloid profiling of the new species Corydalis huangshanensis and other 13 medicinal plants in genus Corydalis."PHYTOCHEMICAL ANALYSIS.2024 Jul;:
47. [IF=4.1] Huaixin Liu et al."A magnetic beads-based ligand fishing method for rapid discovery of monoterpene indoles as monoamine oxidase A inhibitors from Hunteria zeylanica."JOURNAL OF CHROMATOGRAPHY A".2024 May;1722:464896
46. [IF=4.9] Xueyu Pu et al."Lipids Extracted from Mycobacterial Membrane and Enveloped PLGA Nanoparticles for Encapsulating Antibacterial Drugs Elicit Synergistic Antimicrobial Response against Mycobacteria."MOLECULAR PHARMACEUTICS".2024;21(5):2238–2249
45. [IF=7.9] Kaifan Hu et al."Effect of Pulsatilla decoction on vulvovaginal candidiasis in mice. Evidences for its mechanisms of action."PHYTOMEDICINE".2024 Mar;:155515
44. [IF=3.4] Jiaping Zhang et al."Effect of the Pulsatilla decoction n-butanol extract on vulvovaginal candidiasis caused by Candida glabrata and on its virulence factors."FITOTERAPIA.2024 Mar;173:105825
43. [IF=7.9] Shan Zhang et al."Enhancing β-Cell Function and Identity in type 2 diabetes: The Protective Role of Coptis deltoidea C. Y. Cheng et Hsiao via Glucose Metabolism Modulation and AMPK Signaling Activation."PHYTOMEDICINE.2024 Jan;:155396
42. [IF=4] Lewen Xiong et al."Study on Antipyretic Properties of Phenolics in Lonicerae Japonicae Flos Based on Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry Combined with Network Pharmacology."JOURNAL OF FOOD BIOCHEMISTRY.2023;2023:8883860
41. [IF=3.4] Rongrong Li et al."Chemical profiles, Differentiation, and Quality evaluation of Radix et Rhizoma Thalictri Foliolosi based on LC-MS."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.10.1016/j.jpba.2023.115747
40. [IF=4.6] Fengge YANG et al."Deciphering chemical and metabolite profiling of Chang-Kang-Fang by UPLC-Q-TOF-MS/MS and its potential active components identification."Chinese Journal of Natural Medicines.2023 Jun;21:459
39. [IF=4.8] Mingyi Yao et al."In situ detection of natural dyes in archaeological textiles by SERS substrates immobilized on the fiber."MICROCHEMICAL JOURNAL.2023 Sep;192:108939
38. [IF=6.5] Wei Liu et al."Genome-wide analysis of bHLH gene family in Coptis chinensis provides insights into the regulatory role in benzylisoquinoline alkaloid biosynthesis."PLANT PHYSIOLOGY AND BIOCHEMISTRY.2023 Aug;201:107846
37. [IF=5.988] Yuanmei Bai et al."Mechanisms of Yajieshaba in the treatment of liver fibrosis through the Keap1-Nrf2 signaling pathway."Frontiers in Pharmacology.2023; 14: 1124015
36. [IF=0] Xiaoming Yin et al."Assessment of alkaloids from the stems of 14 Berberis species in China."Separation Science Plus.2022 Dec;:202200114
35. [IF=5.195] Kaifan Hu et al."Effects of n-butanol extract of Pulsatilla decoction on the NLRP3 inflammasome in macrophages infected with Candida albicans."JOURNAL OF ETHNOPHARMACOLOGY.2022 Dec;:116041
34. [IF=7.291] Yu Yuetong et al."Functional characterization and key residues engineering of a regio-promiscuity O-methyltransferases involved in benzylisoquinoline alkaloid biosynthesis in Nelumbo nucifera."Horticulture Research.2022 Dec;:
33. [IF=2.838] Wang Shuo et al."Toxicity and toxicokinetics of the ethanol extract of Zuojin formula."BMC Complementary Medicine and Therapies.2022 Dec;22(1):1-14
32. [IF=3.614] Huanyu Guan et al."Deciphering the chemical constituents of Shengjiang Xiexin decoction by ultra-high-performance liquid chromatography-quadrupole/orbitrap high-resolution mass spectrometry and the impact of 20 characteristic components on multidrug resis
31. [IF=7.291] Bu Junling et al."Catalytic promiscuity of O-methyltransferases from Corydalis yanhusuo leading to the structural diversity of benzylisoquinoline alkaloids."Horticulture Research.2022 Jul;:
30. [IF=5.165] Juanning Ren et al."Qualitative and quantitative analysis of multi-components in Xing-Su-Ning Capsules for quality improvement."Arab J Chem. 2022 Jun;15:103825
29. [IF=2.351] Juanjuan Liu et al."Antifungal evaluation of traditional herbal monomers and their potential for inducing cell wall remodeling in Candida albicans and Candida auris."Biofouling. 2020;36(3):319-331
28. [IF=3.004] Kai Zhang et al."Untargeted metabolomics reveals the synergistic mechanisms of Yuanhu Zhitong oral liquid in the treatment of primary dysmenorrhea."J Chromatogr B. 2021 Feb;1165:122523
27. [IF=3.463] Xiao-Meng Liu et al."Comparative transcriptome analysis provides novel insights into the molecular mechanism of berberine biosynthesis in Coptis chinensis."Sci Hortic-Amsterdam. 2022 Jan;291:110585
26. [IF=3.935] Meng Chen et al."Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate."J Pharmaceut Biomed. 2021 Feb;195:113820
25. [IF=3.963] Zhong-min Zhao et al."Anti-phytopathogenic activity and the possible mechanisms of action of isoquinoline alkaloid sanguinarine."Pestic Biochem Phys. 2019 Sep;159:51
24. [IF=11.413] Sifan Luo et al."Rapid identification and isolation of neuraminidase inhibitors from mockstrawberry (Duchesnea indica Andr.) based on ligand fishing combined with HR-ESI-Q-TOF-MS."Acta Pharm Sin B. 2020 Oct;10:1846
23. [IF=1.618] Li Jiang-Yan et al."Seasonal Variation of Alkaloid Contents and Anti-Inflammatory Activity of Rhizoma coptidis Based on Fingerprints Combined with Chemometrics Methods."J Chromatogr Sci. 2015 Aug;53(7):1131-1139
22. [IF=2.419] Kun Wang et al."Identification of metabolites of palmatine in rats after oral administration using ultra-high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry."Rapid Commun Mass Sp. 2017 Mar;31(6):523-537
21. [IF=2.882] Kun Wang et al."Identification of berberrubine metabolites in rats by using ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry."Fitoterapia. 2018 Jan;124:23
20. [IF=3.361] Huanyu Guan et al."Comparative intestinal bacteria-associated pharmacokinetics of 16 components of Shengjiang Xiexin decoction between normal rats and rats with irinotecan hydrochloride (CPT-11)-induced gastrointestinal toxicity in vitro using salting-out
19. [IF=3.935] Kun Wang et al."Metabolites identification of berberine in rats using ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry."J Pharmaceut Biomed. 2017 May;139:73
18. [IF=3.935] Ka-Yan Kwok et al."Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography."J Pharmaceut Biomed. 2013 Nov;85:239
17. [IF=4.411] Jinjun Shan et al."Liquid Chromatography Coupled with Linear Ion Trap Hybrid OrbitrapMass Spectrometry for Determination of Alkaloids in Sinomeniumacutum."Molecules. 2018 Jul;23(7):1634
16. [IF=4.759] Yanyan Zhang et al."Rapid screening and identification of monoamine oxidase-A inhibitors from Corydalis Rhizome using enzyme-immobilized magnetic beads based method."J Chromatogr A. 2019 May;1592:1
15. [IF=6.023] Ling Zhu et al."Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, and HPLC–MS analysis of its chemical composition."Food Chem Toxicol. 2012 Jul;50:2584
14. [IF=6.057] Zhihong Li et al."New MS network analysis pattern for the rapid identification of constituents from traditional Chinese medicine prescription Lishukang capsules in vitro and in vivo based on UHPLC/Q-TOF-MS."Talanta. 2018 Nov;189:606
13. Chen, Meng, et al. "Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate." Journal of Pharmaceutical and Biomedical Analysis 195 (2021): 113820.https:##
12. Wang, Kun, et al. "Metabolites identification of berberine in rats using ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry." Journal of pharmaceutical and biomedical analysis 139 (2017): 73-86.https:##doi.org/10.1016/
11. Wang, Kun, et al. "Identification of metabolites of palmatine in rats after oral administration using ultra‐high‐performance liquid chromatography/quadrupole time‐of‐flight mass spectrometry." Rapid Communications in Mass Spectrometry 31.6 (2017): 523-537.
10. Zhu, Ling, et al. "Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, and HPLC–MS analysis of its chemical composition." Food and chemical toxicology 50.7 (2012): 2584-2588.https:##doi.org/10.1016/j.fct.2012.04.0
9. 纪万里,周泽华,王婷婷,安叡,梁琨,王新宏.基于UPLC-LTQ-Orbitrap-MS方法分析半夏泻心汤化学成分[J].药物分析杂志,2020,40(10):1736-1750.
8. 李听弦 李蒙 张志 等. 一测多评法测定不同味连饮片中6个生物碱类成分的含量[J]. 药物分析杂志 2018 038(007):1132-1138.
7. 张久旭, 范晶, 李小阳,等. 基于内在品质的黄连药材现代产地加工方法研究[J]. 辽宁中医药大学学报, 2019, v.21;No.185(09):74-77.
6. 李听弦, 李蒙, 张志,等. 基于高效液相色谱指纹图谱及红外光谱评价黄连及其炮制品质量差异[J]. 中南药学, 2019, 017(004):556-560.
5. 皮文霞 朱鑫仙 方婷 等. HPLC同时测定"三热论"方各纯化部位中药根碱、表小檗碱、黄连碱、巴马汀和小檗碱的含量[J]. 中国实验方剂学杂志 2012 18(14):110-113.
4. 严赟, 张赟赟. HPLC-ESI-MS/MS同时测定金果榄中5种成分含量[J]. 中药材, 2017, 40(002):395-398.
3. 张赟赟,李嘉.HPLC-ESI-MS/MS法同时测定金线风中7种有效成分[J].中华中医药杂志,2017,32(06):2762-2764.
2. 王书宁, 祝洪艳, 郜玉钢,等. 黄藤总生物碱回流提取工艺的优化[J]. 中成药, 2018, 040(006):1399-1403.
1. 林才志, 张贇赟, 段雪琳,等. 壮药汗衣台抗HBV有效成分分析及对HBVDNA、HBVcccDNA的影响[J]. 中药药理与临床, 2018, v.34;No.193(01):59-64.
。 6.掌握四氢巴马汀的制备方法。 黄藤中已知成分的理化性质: 黄藤根茎及根中所含成分主为巴马汀。尚含少量药根碱、黄藤素甲、黄藤素乙、内脂及甾醇。又谓在根茎、根及树皮中含小檗碱。 1. 掌叶防已碱(巴马汀,Palmatine) 本品系季铵生物碱,溶于水、乙醇,几乎不溶于氯仿、乙醚、苯等溶剂,掌叶防已碱盐酸盐即氯化巴马汀(palmation Chloride)C21H22O4N ·Cl·3H2O为黄色针状结晶,熔点205℃(分解)。其理化性质与盐酸小檗碱类似。巴马汀氢
汀的Rf值一致,如反应不彻底则出现二个斑点,其Rf值分别与对照品巴马汀及四氢巴马汀一致。黄藤中生成碱的检识: 1.生物碱沉淀反应 取黄藤的15醋酸浸出液每份1ml,置小试管中,分别滴加下列各试剂2~3滴,观察并记录有无沉淀产生及颜色变化。 (1)碘化铋钾试剂 (2)硅钨酸试剂 (3)苦味酸试剂(样品液需调至中性) (4)鞣酸试剂 2.薄层层析 硅胶-CMC- Na薄层 样品 巴马汀,小檗碱,药根碱,延胡索乙素,制备巴马汀后的母液,盐析后的水母液展开剂氯仿-甲醇
)、药根碱(jatrorrhizine)、小檗胺(berbemine)和尖刺碱(oxyacanthine)等,均具有多种生理活性。八角莲属、山荷叶属和桃儿七属植物,均含鬼臼脂素(podophyllo-toxin)和山荷叶素(diphyllin)等,对多种癌症有一定效果。但鬼臼脂素毒性太大,临床应慎用。小檗属和十大功劳属的一些种也是著名的观赏植物和小麦秆锈病越冬孢子的转主寄主。 有人把本科分为鬼臼亚科(Podophylloideae)和小檗亚科(Berberideae)。前者以花无蜜腺
技术资料暂无技术资料 索取技术资料









