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- MedChemExpress(MCE)
- 美国
- HY-U00387
- 2025年12月05日
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Please store the product under the recommended conditions in the Certificate of Analysis.
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货期：询盘
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MedChemExpress LLC
- CAS号：
137004-80-9
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1 mg
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CCK-A receptor inhibitor 1
CAS No. : 137004-80-9
MCE 国际站：CCK-A receptor inhibitor 1
产品活性：CCK-A receptor inhibitor 1 是一种缩胆囊素 A (cholecystokinin A, CCK-A) 受体抑制剂，IC50 为 340 nM。
研究领域：GPCR/G Protein | Neuronal Signaling
作用靶点：Cholecystokinin Receptor
In Vitro: CCK-A receptor inhibitor 1 (Compound 7c) is a naphthyl sulfone derivative, which is synthesized and tested for cholecystokinin A (CCK-A) receptor inhibitory activity in order to study structure-activity relationships. Significant CCK-A receptor inhibitory activities are found in CCK-A receptor inhibitor 1 having very hydrophobic sidechains.
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文献和实验Characterization of Cholecystokinin (CCK) Receptors
Sciences; preferred radioligand for this procedure) [125 I‐Tyr12 ]human gastrin‐I (high‐affinity radiolabeled CCK 2 receptor agonist with low affinity for the CCK 1 receptor; 2200 Ci/mmol
Receptor Tyrosine Kinase Inhibitor Profiling Using Bead-Based Multiplex Sandwich Immunoassays
Receptor tyrosine kinases (RTK) are important targets in drug discovery processes. Studying the phosphorylation pattern of RTKs enables the determination of their activation and inactivation states. Multiplex bead-based sandwich immunoassays
with FGF signaling by treating embryos with SU5402 (Calbiochem), a FGF receptor inhibitor. We observed craniofacial deformities and delayed maturation in embryos treated with SU5402. this indicates that FGF signaling is required for cranifacial formation
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