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- PeproTech
- 400-16L
- 美国
- 2025年07月07日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
PeproTech(派普泰克)
- 库存：
大量
- 英文名：
Recombinant Rat IL-13 (Long Form)
| Synonyms : |
NC300 (Human) P600 (Murine) |
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| Description : |
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Recombinant rat IL-13 is a 12.3 kDa protein consisting of 113 amino acid residues. |
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| Catalog #: |
400-16L |
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| Source : |
E.coli |
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| Purity : |
Greater than 98% by SDS-PAGE gel and HPLC analyses. |
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| Endotoxin Level : |
Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
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| Biological Activity : |
The ED 50 was determined by the dose-dependent proliferation of TF-1 cells is < 5.0 ng/ml, corresponding to a specific activity of > 2 x 105 units/mg. |
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| AA Sequence : |
TPGPVRRSTS PPVALRELIE ELSNITQDQK TSLCNSSIVW SVDLTAGGFC AALESLTNIS SCNAIHRTQR ILNGLCNQKA SDVASSPPDT KIEVAQFISK LLNYSKQLFR YGH |
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| PubMed Link : |
IL-13+AND+rat |
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| Country of Origin : |
USA |
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SQ Blood Mini Protocol for 50ul Clotted Blood
may be visible after vortexing. Incubate in ice for 5 minutes. 8. Centrifuge at max speed for 3 minutes at room temperature. The precipitated protein will form a tight, dark brown pellet. If the pellet is not tight or visible, incubate the tube in ice
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