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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
PeproTech(派普泰克)
- 库存:
大量
- 英文名:
Recombinant Human IL-15
| Synonyms : |
IL-T |
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| Description : |
IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant human IL-15 is a 12.9 kDa protein consisting of 114 amino acid residues. |
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| Catalog #: |
200-15 |
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| Source : |
E.coli |
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| Purity : |
Greater than 98% by SDS-PAGE gel and HPLC analyses. |
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| Endotoxin Level : |
Endotoxin level is less than 0.1 ng per µg (1EU/µg). |
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| Biological Activity : |
The ED 50 as determined by the dose-dependent stimulation of the proliferation of CTLL-2 cells was found to be ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. |
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| Selected References : |
Selected List of References Citing This Product |
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| AA Sequence : |
MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS |
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| PubMed Link : |
IL-15 |
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| Country of Origin : |
USA |
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上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 大鼠白介素 -15(IL-15)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗大鼠 IL-15 单抗包被于酶标板上,标准品和样品中的 IL-15 与单抗结合,加入生物素化的抗大鼠 IL-15 ,形成免疫复合物连接
白细胞介素 IL-15 IL 15主要产生细胞:单核细胞、巨噬细胞、胎盘、肌肉组织 IL 15氨基酸数目:114 IL 15分子质量(kDa):14~18 IL 15受体:1L-15R;CDl22;CDl32(γc) IL 15主要生物学活性:刺激活化T细胞,趋化T细胞,诱导CTL产生和促进其杀伤活性;诱导NK细胞的早期分化,刺激NK增殖、杀伤和细胞因子产生;刺激活化B
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