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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
PeproTech(派普泰克)
- 库存:
大量
- 英文名:
Recombinant Human IL-17D
| Synonyms : |
IL-27 |
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| Description : |
IL-17D is a disulfide-linked homodimer of two 185 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8, and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays. Recombinant human IL-17D is a 40.5 kDa disulfide-linked homodimer of two 185 amino acid polypeptide chains. |
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| Catalog #: |
200-27 |
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| Source : |
E.coli |
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| Purity : |
Greater than 98% by SDS-PAGE gel and HPLC analyses. |
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| Endotoxin Level : |
Endotoxin level is less than 0.1 ng per µg (1EU/µg). |
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| Biological Activity : |
Testing in progress. |
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| AA Sequence : |
APRAGRRPAR PRGCADRPEE LLEQLYGRLA AGVLSAFHHT LQLGPREQAR NASCPAGGRP ADRRFRPPTN LRSVSPWAYR ISYDPARYPR YLPEAYCLCR GCLTGLFGEE DVRFRSAPVY MPTVVLRRTP ACAGGRSVYT EAYVTIPVGC TCVPEPEKDA DSINSSIDKQ GAKLLLGPND APAGP |
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| PubMed Link : |
IL-17D |
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| Country of Origin : |
USA |
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文献和实验Immunity:「填补教科书」董晨院士团队解析 IL-17D 重要功能,并首次发现其受体
慢性炎症与自身免疫性疾病、过敏性疾病和肿瘤的发展密切相关,炎性因子白介素 - 17(IL-17)家族在促进宿主防御和自身免疫性疾病中起着重要作用。IL-17 家族由六个成员组成(包括 IL-17A、B、C、D、E、F),IL-17D 是 IL-17 家族中了解最少的成员,其受体也尚不明确。 图片来源:Frontiers in Immunology(1)2021 年 4 月 13 日,清华大学医学院董晨院士团队在 Immunity 上在线发表了题为 Interleukin-17D
「丁香实验」小程序上线后,已经汇集上万条实验 protocol、常见操作问答、科研方法文章等。 为了能给科研人带来更多的交流与互助,现开展一期「WB 实验大赛」。 晒出你的实验方法和结果图( beta-actin 或者其他内参均可)就有机会瓜分 1000 元现金奖! 你将会获得 丰富奖金上至 500元/人、丰富的科研周边、建立个人专题打造个人 IP 、增加实验室曝光、论文引用机会! 我们希望你 有着丰富的 WB 实验经验,实验优化小建议,并愿意分享自己的经验
Plasmid Preparation on Sephacryl S1000
Production of pure plasmid DNA is a prerequisite for most laboratories engaged in recombinant DNA research. There are a number of procedures available for plasmid purification, all of which have common features; namely, (1 ) growth of plasmid
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