- 询价
- PEPROTECH
- AF-120-04-10
- 美国
- 2025年09月20日
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- 详细信息
- 技术资料
- 库存：
大量
- 供应商：
PeproTech(派普泰克)
- 英文名：
Recombinant Human BMP-13/CDMP-2
- 规格：
10ug
Catalog Number:
AF-120-04
Synonyms:
Bone Morphogenetic Protein-13, GDF-6, Cartilage-Derived Morphogenetic Protein-2 (CDMP-2)
Description:
BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino-acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7kDa. Recombinant Human BMP-13/CDMP-2 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains. Manufactured using all Animal-Free reagents.
AA Sequence:
TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR
Source:
E.coli
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 2.0-3.0 μg/ml.
Research Interests:
 |
Angiogenesis/ Cardiovascular |  |
Apoptosis |
 |
Bone, Skeletal, Cartilage |  |
Proliferation |
 |
Stem Cells & Differentiation |  |
TGF-β Superfamily |
Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.
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PeproTech重组人BMP-13/CDMP-2 （无动物成分）10ug
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