A gut-derived hormone regulates cholesterol metabolism.
Cell(2024)Cholesin基因敲除小鼠
Myocardial infarction drives trained immunity of monocytes, accelerating atherosclerosis.
Eur Heart J(2024)Apoe基因敲除小鼠
Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor).
Signal Transduction and Targeted Therapy(2024)Zbtb18条件性敲除小鼠
Disruption of the Na/K-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety.
Immuntiy(2024)Atp1a1条件性敲除小鼠
Sensory neurons promote immune homeostasis in the lung.
Cell(2023)Jak1条件性敲除小鼠
Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell(2023)Taar1基因敲除小鼠、Taar1条件性敲除小鼠
Rhythmic cilia changes support SCN neuron coherence in circadian clock.
Science(2023)Shh条件性敲除小鼠
NAD exhaustion by CD38 upregulation contributes to blood pressure elevation and vascular damage in hypertension.
Signal Transduction and Targeted Therapy(2023)Cd38基因敲除小鼠
Bacteria-derived nanovesicles enhance tumour vaccination by trained immunity.
Nature Nanotechnology(2023)Casp4基因敲除小鼠
Post-translational control of beige fat biogenesis by PRDM16 stabilization.
Nature(2022)Appbp2条件性敲除小鼠