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- 详细信息
- 技术资料
- 保存条件：
Pure form: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
HCT 1206; NO-flurbiprofen; Nitroxybutyl flurbiprofen
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
158836-71-6
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥2703.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥1600.0 |
| 规格： | 5 mg | 产品价格： | ￥3400.0 |
| 规格： | 10 mg | 产品价格： | ￥4700.0 |
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Nitroflurbiprofen
CAS No. : 158836-71-6
MCE 国际站：Nitroflurbiprofen
产品活性：Nitroflurbiprofen 是一种环氧合酶 (COX) 抑制剂。
作用靶点：COX
In Vivo: In vivo hemodynamic measurements (n = 8/condition) and evaluation of the increased intrahepatic resistance by in situ perfusion (n=5/condition) are performed in rats with thioacetamide-induced cirrhosis that receive either Nitroflurbiprofen (45 mg/kg), Flurbiprofen (30 mg/kg, equimolar concentration to Nitroflurbiprofen), or vehicle by intraperitoneal injection 24 hours and 1 hour prior to the measurements. Treatment with Nitroflurbiprofen, an NO-releasing cyclooxygenase inhibitor, improves portal hypertension without major adverse effects in thioacetamide-induced cirrhotic rats by attenuating intrahepatic vascular resistance, endothelial dysfunction, and hepatic hyperreactivity to vasoconstrictors.
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