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文献和实验Fibrinogen is the final essential building block of the clotting process. Thus, all of the preliminary “cause and effect” events in the clotting cascade rely on the work of this molecule to measure their success. The most commonly used
Ligand-Binding Assays: Fibrinogen
The fibrinogen receptor on platelets is glycoprotein (GP) IIb/IIIa, also known as αIIb β3 . This receptor can bind to immobilized fibrinogen in its resting state. Binding to soluble fibrinogen, however, requires activation of the receptor
D-Dimer and Fibrinogen/Fibrin Degradation Products
Although clinical requests for D-dimer are generally in the minority of assays in the routine clinical laboratory, they are an important aspect—especially if the laboratory supports an active emergency room and hematology service
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