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文献和实验Therapeutic Human Monoclonal Antibodies in Inflammatory Diseases
(anti-TNF), anti-interleukin-1 (anti-IL-1) receptor, anti-IL-6 receptor, anti-α4 integrin subunit, and anti-CD20 agents, all of which have been documented by clinical trials to be efficacious and have been approved for the therapy of several inflammatory
Primary Culture and Differentiation of Human Adipocyte Precursor Cells
in the regulation of energy homeostasis and a variety of neuroendocrine, metabolic, and immune functions (3 -5 ). The cytokines leptin, tumor necrosis factor-α (TNF-α), interleukin 6 (IL-6), as well as angiotensinogen and plasminogen activator inhibitor-1 (PAI
28 Large-Scale Ex Vivo Expansion of Human Megakaryocytes for Clinical Use
progenitor cells requires specific combinations of cytokines to promote their proliferation and maturation in vitro. Thrombopoietin (TPO) is the primary regulator of megakaryocytopoiesis (1 -6 ). Other cytokines, including interleukin-3 (IL-3), IL-6, IL
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