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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
低温
- 保质期:
2年
- 英文名:
Recombinant Mouse Fas Ligand/TNFSF6 Protein
- 库存:
大量
- 供应商:
北京百奥创新科技有限公司
- 规格:
具体价格请联系我们
Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Endotoxin Level:<0.01 EU per 1 μg of the protein by the LAL method.
Activity:Measured by its ability to induce apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is 1-8 ng/mL in the presence of 2.5 µg/mL of a cross-linking antibody, Mouse Anti-Hemagglutinin/HA Peptide Monoclonal Antibody (Catalog # MAB060).
Source:Chinese Hamster Ovary cell line, CHO-derived mouse Fas Ligand/TNFSF6 protein
| Hemagglutinin Tag (YPYDVPDYA) | GCN4-IZ | (GGGS)3 | Mouse Fas Ligand (Gln101-Leu279) Accession # P41047 |
N-terminus C-terminus
N-terminal Sequence Analysis:Tyr
Predicted Molecular Mass:25.9 kDa (monomer)
SDS-PAGE:40-55 kDa, reducing conditions

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文献和实验北京百奥创新科技有限公司
带有死亡结构域的Fas 结合蛋白 带有死亡结构域的Fas结合蛋白(Fas-associating protein with death domain,FADD)是分子质量为23kDa的胞质蛋白质。人类FADD基因编码区长约2.6kb,有2个外显子,其间被一长约2kb的内含子分隔。外显子1长286bp,编码N端诱导细胞凋亡所必须的死亡效应结构域(deatheffectdomain,DED);外显子2长341bp,编码死亡结构域(DD),此DD基因与Fas
Preparation of Recombinant Protein Spotted Arrays for Proteome‐Wide Identification of Kinase Targets
, M., and Snyder, M. 2011. Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes. Genes Dev. 25:767‐778.
(9 ). Because its systemic administration was shown to mediate the regression of some mouse tumors (10 ), TNF-α has attracted much attention as a potential antitumor reagent (11 ). However, the problem of its dose-dependent toxicity has been particularly apparent in human
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