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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Ubiquitin-protein ligase E3C protein (310-377AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
Biotin
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q15386
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA
- 浓度:
>95%,Protein G purified
- 靶点:
UBE3C
- 抗体英文名:
UBE3C Antibody, Biotin conjugated
- 抗体名:
HectH2 antibody;KIAA0010 antibody;KIAA10 antibody;Ube3c antibody;UBE3C_HUMAN antibody;Ubiquitin protein isopeptide ligase (E3) antibody;Ubiquitin protein ligase E3C antibody;Ubiquitin-protein ligase E3C antibody
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验的既有鼠源成分,又有人源成分的抗体称为人源化抗体(humanized antibody)。人源化 抗体是通过基因工程制备的,所以又可称为基因工程抗体(genetically engineered antibody)。人源化抗体 的优越性主要表现在于其不会激起快速的抗球蛋白反应。由于Fc 段来源于人,其能更有效的与人体免疫 系统协同发挥作用。 嵌合抗体 由于90%的HAMA 是针对抗体C 区的,设计从分泌鼠McAb 的杂交瘤细胞基因组中分离功能性IgV 区基因,然后与人C 区基因按一定方式拼接
, or as often as necessary to decrease the background. Pellet cells. Save antibody supernatant, which is now diluted 1:5 from its initial concentration. These antibodies can be stored at 4o C for several weeks or at -70o C for longer periods. Solutions
Combined 3C-ChIP-Cloning (6C) Assay: A Tool to Unravel Protein-Mediated Genome Architecture
between chromatin elements without specifically identifying the protein components that mediate such interactions. Here we describe a detailed protocol for C ombined 3C -C hIP-C loning (6C) technology, which combines multiple techniques to identify the proteins
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