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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Candida glabrata Autophagy-related protein 8 protein (1-116AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
FITC
- 适应物种:
Candida glabrata
- 保质期:
6个月
- 抗原来源:
Candida glabrata
- 目录编号:
Q6FXR8
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
/
- 浓度:
>95%,Protein G purified
- 靶点:
ATG8
- 抗体英文名:
ATG8 Antibody, FITC conjugated
- 抗体名:
ATG8 antibody;AUT7 antibody;CAGL0A04675gAutophagy-related protein 8 antibody;Autophagy-related ubiquitin-like modifier ATG8 antibody
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. With ATG4, mediates the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验各种各样的问题,包括神经元堵塞。”Vierstra指出,CDC48以六聚体形式存在,即使复合物中有一个错误的拷贝,也会搅乱自噬。“正如人们所说,一个坏苹果会毁了整个桶,”Vierstra说。“在一些神经系统疾病中,只要有一个缺陷的CDC48出错,就会产生不良后果,如果你不能及时清理它制造的混乱。”原文检索:ATG8-Binding UIM Proteins Define a New Class of Autophagy Adaptors and Receptors③ miRNA与癌症关联研究全
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