PIK3R1抗体PIK3R1兔多抗抗体PtdIns-3-ki
nase regulatory subunit p85-alpha antibody抗体PIK3R1 Antibody, Biotin conjugated抗体- ￥880 - 1320
- CUSABIO
- CN
- CSB-PA018003LD01HU
- 2025年07月12日
- ELISA
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human Phosphatidylinositol 3-kinase regulatory subunit alpha protein (160-376AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Biotin
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
P27986
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA
- 浓度：
>95%,Protein G purified
- 靶点：
PIK3R1
- 抗体英文名：
PIK3R1 Antibody, Biotin conjugated
- 抗体名：
PtdIns-3-kinase regulatory subunit p85-alpha antibody
- 规格：
100μg/50μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling (PubMed:17626883, PubMed:19805105, PubMed:7518429). Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress-and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (PubMed:20348923).风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Two-hybrid analysis of genetic regulatory networks
with antibodies to its epitope tag, is expressed at the same level in each diploid, and that the baits, which can be detected with anti-LexA antibody and whose DNA binding can be quantitated by a repression assay (Brent and Ptashne, 1984), occupy the operators
on the PI3K p85 regulatory subunit, or the adaptor proteins IRS1 and IRS2. IRS1 and IRS2 are phosphorylated by the activated receptor, generating docking sites for the SH2 domains of p85 and inducing proper assembly of the signalling complex. These SH2–
血管里的“斑块清洁工”来了！CD25+调节性T细胞变身CAR-Treg，效果惊人
于对机体免疫调节机制的了解，最终为相关疾病的治疗开辟新的免疫治疗途径。 为鼎力协助科研和药企人员针对IL-2RA（CD25）在多种免疫疾病和肿瘤中的临床应用研究，CUSABIO推出IL-2RA（CD25）活性蛋白（Code: CSB-MP011649HU3），助力您在IL-2RA（CD25）机制方面的研究或其潜在临床价值的探索。 ● IL-2RA（CD25）蛋白 Recombinant Human Interleukin-2 receptor subunit alpha(IL2RA),partial
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