PPOX抗体PPOX一抗抗体VP antibody抗体PPO

保存缓冲液

-20℃, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

功能

This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.