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- CUSABIO
- CN
- CSB-PA186422
- 2025年07月12日
- ELISA,WB,IHC;WB:1:500-1:1000,IHC:1:50-1:200
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Peptide sequence around aa.1421~1425 (H-G-S-Q-P) derived from Human BRCA1.
- 亚型：
/
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
/
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
P38398
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA,WB,IHC;WB:1:500-1:1000,IHC:1:50-1:200
- 浓度：
>95%,Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 靶点：
BRCA1
- 抗体英文名：
BRCA1 (Ab-1423) Antibody
- 抗体名：
/
- 规格：
100μl
保存缓冲液
/功能
The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Plays a central role in DNA repair by facilitating cellular response to DNA repair. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Involved in transcriptional regulation of P21 in response to DNA damage. Required for FANCD2 targeting to sites of DNA damage. May function as a transcriptional regulator. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation
Kim ST, et al. (2002) Genes Dev; 16(5): 560-570
Arlt MF, et al. (2004) Mol Cell Biol; 24(15): 6701-6709
Zhang J, et al. (2004) Mol Cell Biol; 24(2): 708-718
Greenberg RA, et al. (2006) Genes Dev; 20(1): 34-46
Tibbetts RS, et al. (2000) Genes Dev; 14(23): 2989-3002
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文献和实验dongreyuan 有的抗体名称上面写着Ab-33，比如，β-catenin（Ab-33）antibody，请问，Ab-33是什么意思？ bettyzyj 这个抗体是非磷酸化的抗体non-phospho-antibody ，33 代表的是基因位点 dongreyuan 谢谢了 yhwangcams bettyzyj wrote
AB0系统的抗体是检验主管技师考试的内容，医学教育网搜集整理相关内容供大家参考。 天然抗体与免疫性抗体：天然抗体是在没有可觉察的抗原刺激下而产生的抗体，以IgM为主，又称完全抗体或盐水抗体；也可能是由一种无觉察的免疫刺激产生而得。免疫性抗体：有IgM、IgG、IgA，但主要是IgG.抗A和抗B可以是IgM与IgG，甚至是IgM、IgG、IgA的混合物，但主要是IgM，而0型血清中以IgG为主。
Production of Bispecif ic and Trispecific F(ab)2 and F(ab)3 Antibody Derivatives
Bispecific antibodies (BsAbs) are hybrid molecules designed to combine two antibodies with different specificities. This dual specificity has led to their application in a variety of diagnostic situations that require the crosslinking
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