DBNDD1 Rabbit pAb(bs-14202R)-50ul/100ul/200ul

DBNDD1 Rabbit pAb(bs-14202R)-5

0ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-14202R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-14202R
    英文名称DBNDD1 Rabbit pAb
    中文名称肌养素结合蛋白1/精神分裂症易感基因抗体
    英文别名DBND1_HUMAN; Dbndd1; Dysbindin(dystrobrevin binding protein 1) domain containing 1; Dysbindin domain-containing protein 1; FLJ12582; MGC3101.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human DBNDD1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量17 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    相似性Belongs to the dysbindin family.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料DBNDD1 is a 158 amino acid member of the dysbindin protein family. DBNDD1 is expressed as three isoforms that are produced by alternative splicing and are encoded by a gene mapping to human chromosome 16. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SGLT-6 as a potential autoimmune modifier.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    DBNDD1 Rabbit pAb(bs-14202R)-5
    P‌‌araformaldehyde-fixed, paraffin embedded (Mouse colon); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DBNDD1) Polyclonal Antibody, Unconjugated (bs-14202R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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