- ￥2980
- Bioss
- bs-22667R-Bio
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
ZNF694 Rabbit pAb(bs-4385R)-50ul/100ul/200ul
￥1180
COMMD4 Rabbit pAb(bs-8037R)-50ul/100ul/200ul
￥1180
phospho-CDK7 (Thr170) Rabbit pAb, APC-Cy7 conjugated(bs-10997R-APC-Cy7)-100ul
￥2980
Amphiregulin Rabbit pAb, PE-Cy5.5 conjugated(bs-3847R-PE-Cy5.5)-100ul
￥2980phospho-CHEK2 (Thr383) Rabbit pAb, PerCP-Cy7 conjugated(bs-13910R-PerCP-Cy7)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-22667R-Bio |
| 英文名称 | IGF2BP2 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的胰岛素样生长因子ⅡmRNA结合蛋白2抗体 |
| 英文别名 | Hepatocellular carcinoma autoantigen p62; IF2B2_HUMAN; IGF 2 mRNA binding protein 2; IGF II mRNA binding protein 2; IGF-II mRNA-binding protein 2; IGF2 mRNA-binding protein 2; Igf2bp2; IMP 2; IMP-2; IMP2; Insulin like growth factor 2 mRNA binding protein 2; Insulin-like growth factor 2 mRNA-binding protein 2; p62; VICKZ family member 2; VICKZ2; IGF2-BP2. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human IGF2BP2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding Epigenetics and Nuclear Signaling > DNA / RNA > Translation > Regulation Immunology > Immune System Diseases > Autoimmune Metabolism > Types of disease > Metabolic disorders Signal Transduction > Growth Factors/Hormones > Insulin / Insulin-like |
| 亚基 | Interacts with HNRPD and IGF2BP1. |
| 亚细胞定位 | Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Localizes at the connecting piece and the tail of the spermatozoa. |
| 组织特异性 | Expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia and semen (at protein level). Expressed in testicular cancer (at protein level). Expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas. Detected in fetal liver, fetal ovary, gonocytes and interstitial cells of the testis. |
| 相似性 | Belongs to the RRM IMP/VICKZ family_x000D_
br>Contains 4 KH domains._x000D_
Contains 2 RRM (RNA recognition motif) domains. |
| 功能 | Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | IGF2BP2 (insulin-like growth factor 2 mRNA binding protein 2) is also known as IGF2 mRNA-binding protein 2, IMP-2 (IGF-II mRNA-binding protein 2), VICKZ family member 2 or hepatocellular carcinoma autoantigen p62 and is a 556 amino acid protein. IGF2BP2 is expressed in a variety of tissues including heart, placenta, skeletal muscle, pancreas, fetal liver, lung, kidney, thymus and gonadal cells. IGF2BP2 is an RNA binding protein which may be involved in the regulation of mRNA translation and may also function to control the spatial localization of target mRNAs. Antibodies against IGF2BP2 have been detected in patients with HCC (hepatocellular carcinoma), suggesting that IGF2BP2 may have a role in the pathogenesis of HCC. Defects in IGF2BP2 are thought to be associated with susceptibility to type 2 diabetes mellitus. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
IGF2BP2 Rabbit pAb, Biotin conjugated(bs-22667R-Bio)-100ul
￥2980
