Sample:
_x000D_
Lane 1: Mouse Cerebrum tissue lysates
_x000D_
Lane 2: Rat Cerebrum tissue lysates
_x000D_
Lane 3: Human HL60 cell lysates
_x000D_
Primary: Anti-GODZ/ZDHHC3 (bs-12034R) at 1/1000 dilution
_x000D_
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_
Predicted band size: 37 kD
_x000D_
Observed band size: 37 kD
- ￥1180 - 2800
- Bioss
- bs-12034R
- 2026年10月14日
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- 技术资料
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-12034R |
| 英文名称 | ZDHHC3 Rabbit pAb |
| 中文名称 | 棕榈酰转移酶GODZ抗体 |
| 英文别名 | DHHC-3; GABA-A receptor-associated membrane protein 1; Golgi-specific DHHC zinc finger protein; Gramp1; Palmitoyltransferase ZDHHC3; Protein DHHC1; ZDHC3_HUMAN; Zdhhc3; Zinc finger DHHC domain-containing protein 3; Zinc finger protein 373; ZNF373. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat (Dog, Pig, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GODZ/ZNF373 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 34 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurotransmission > Intracellular Signaling > Regulation Neuroscience > Neurotransmission > Receptors / Channels > GPCR > Glutamate Receptors Neuroscience > Neurotransmitter > Transporters > GABA Signal Transduction > Protein Trafficking > Golgi Proteins Signal Transduction > Protein Trafficking > Organelle Proteins |
| 亚细胞定位 | Golgi apparatus membrane. |
| 翻译后修饰 | Autopalmitoylated. |
| 相似性 | Belongs to the DHHC palmitoyltransferase family. _x000D_ Contains 1 DHHC-type zinc finger. |
| 功能 | Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Golgi-specific DHHC (Asp-His-His-Cys) zinc finger protein (GODZ), also known as, Palmitoyltransferase ZDHHC3 or Zinc finger protein 373, is a 327 amino acid protein member of the DHHC palmitoyltransferase family. Localized to the Golgi apparatus membrane, GODZ contains one DHHC-type zinc finger, which is necessary for its palmitoyltransferase activity. GODZ has been implicated in the palmitoylation and regulated trafficking of diverse substrates that function various inhibitory and excitatory synapses. Specifically, it palmitoylates the gamma subunit 2 of GABA(A) receptors, which leads to normal synaptic GABAergic inhibitory function. GODZ also palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. Two isoforms of GODZ exist as a result of alternative splicing events. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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ZDHHC3 | DHHC-3 Rabbit pAb(bs-12034R)-50ul/100ul/200ul
￥1180 - 2800
