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- bs-9242R
- 2025年10月24日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-9242R |
| 英文名称 | RNF34 Rabbit pAb |
| 中文名称 | 环指蛋白34抗体 |
| 英文别名 | Caspase regulator CARP1; CARP 1; CARP-1; CARP1; Caspase regulator CARP1; Caspases-8 and-10-associated RING finger protein 1; E3 ubiquitin-protein ligase RNF34; FYVE-RING finger protein Momo; hRFI; Human RING finger homologous to inhibitor of apoptosis protein; RFI; RIF; RIFF; RING finger protein 34; RING finger protein RIFF; RNF34; RNF34_HUMAN. |
| 产品应用 | ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human RNF34 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 42 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > RING Finger E3 Ligase |
| 亚基 | Interacts with DNAJA3 (Potential). Interacts with CASP8 and CASP10. |
| 亚细胞定位 | Nucleus speckle. Endomembrane system; Peripheral membrane protein. |
| 组织特异性 | Ubiquitous. Detected in heart, brain, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, colon and leukocytes. |
| 翻译后修饰 | Auto-ubiquitinated (in vitro) (By similarity). Proteolytically cleaved by caspases upon induction of apoptosis by TNF. |
| 相似性 | Contains 1 FYVE-type zinc finger. Contains 1 RING-type zinc finger. Contains 2 SAP domains. |
| 功能 | Has E3 ubiquitin-protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Protects cells against apoptosis induced by TNF. Binds phosphatidylinositol 5-phosphate and phosphatidylinositol 3-phosphate. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Has E3 ubiquitin-protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Protects cells against apoptosis induced by TNF. Binds phosphatidylinositol-5-phosphate and phosphatidylinositol-3-phosphate. |
| 应用 | 推荐稀释比例 |
| {ELISA} | {1:5000-10000} |
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文献和实验= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
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Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
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