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LRP5L Rabbit pAb(bs-11590R)-50

ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-11590R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-11590R
    英文名称LRP5L Rabbit pAb
    中文名称低密度脂蛋白受体5样蛋白抗体
    英文别名Low-density lipoprotein receptor-related protein 5-like protein; LRP-5-like; LRP5L; GP330; LRP5L_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Chicken, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human LRP5L
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量28 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Developmental Biology > Embryogenesis > Axis formation and symmetry

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families

    相似性Contains 5 LDL-receptor class B repeats.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Members of the LDL receptor gene family, including LDLR (low density lipo-protein receptor), LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. Of the known family members, LRP5 is most closely related to LRP1. However, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family. LRP is expressed in rat tibia, specifically in areas of the bone that are involved in remodeling. LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway. LRP5 affects bone mass accrual during growth. Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG). LRP5L is a related protein that exists as two isoforms produced by alternative splicing.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    U2os(Human) Cell Lysate at 30 ug
    293T(Human) Cell Lysate at 30 ug
    Primary: Anti-LRP5L (bs-11590R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 28 kD
    Observed band size: 28 kD
    产品细节图片2
    Sample:
    U2OS(Human) Cell Lysate at 30 ug
    Primary: Anti- LRP5L (bs-11590R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 28 kD
    Observed band size: 28 kD

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    LRP5L Rabbit pAb(bs-11590R)-50ul/100ul/200ul
    ¥1180 - 2800