Insulin (1G11) Mouse mAb(bsm-0855M)-50ul/100ul/200ul/200ug

Insulin (1G11) Mouse mAb(bsm-0

855M)-50ul/100ul/200ul/200ug
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  • ¥1180 - 5600
  • Bioss已认证
  • bsm-0855M
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul/200ug

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    规格:200ug产品价格:¥5600.0
    产品编号bsm-0855M
    英文名称Insulin (1G11) Mouse mAb
    中文名称胰岛素单克隆抗体
    英文别名ILPR; INS; Insulin A chain; Insulin B chain; Insulin A chain; Insulin precursor; IRDN; Proinsulin; Proinsulin precursor; IDDM2; INS_HUMAN; MODY10.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Pig)
    抗体来源Mouse
    免疫原Recombinded human Insulin protein
    亚型IgG1
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Monoclonal
    理论分子量5.8/12 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Atherosclerosis > Diabetes associated

    Metabolism > Types of disease > Diabetes

    Metabolism > Types of disease > Heart disease

    Metabolism > Types of disease > Obesity

    Neuroscience > Neurology process > Metabolism

    Signal Transduction > Growth Factors/Hormones > Insulin / Insulin-like

    亚基Heterodimer of a B chain and an A chain linked by two disulfide bonds.
    亚细胞定位Secreted.
    相似性Belongs to the insulin family.
    功能Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    Insulin (1G11) Mouse mAb(bsm-0
    Sample:
    Lane 1: Human ASPC-1 cell lysates
    Primary: Anti-Insulin (bsm-0855M) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
    Predicted band size: 5.8/12 kDa
    Observed band size: 10 kDa

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