Sample: Hcclm3 Cell (Human) Lysate at 40 ug
Primary: Anti-Fibrinogen gamma chain (bs-6895R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kD
Observed band size: 60 kD
- ￥1180 - 2800
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- bs-6895R
- 2025年10月16日
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-6895R |
| 英文名称 | Fibrinogen gamma chain Rabbit pAb |
| 中文名称 | 纤维蛋白原γ链抗体 |
| 英文别名 | FGG; FIBG_HUMAN; Fibrinogen gamma chain; Fibrinogen gamma polypeptide; fibrinogen gamma-b chain. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat (Dog, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Fibrinogen gamma chain |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 47 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain. |
| 亚细胞定位 | Secreted. |
| 翻译后修饰 | Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. The soft clot is converted into the hard clot by factor XIIIA which catalyzes the epsilon-(gamma-glutamyl)lysine cross-linking between gamma chains (stronger) and between alpha chains (weaker) of different monomers. Sulfation of C-terminal tyrosines increases affinity for thrombin. |
| 相似性 | Contains 1 fibrinogen C-terminal domain. |
| 功能 | Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.Involvement in disease: Defects in FGG are a cause of thrombophilia.Defects in FGG are a cause of congenital afibrinogenemia (CAFBN). It is a rare autosomal recessive disorder characterized by complete absence of detectable fibrinogen. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample: BRL-3A Cell (Rat) Lysate at 40 ug
Primary: Anti-Fibrinogen gamma chain (bs-6895R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kD
Observed band size: 60 kD
Primary: Anti-Fibrinogen gamma chain (bs-6895R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kD
Observed band size: 60 kD
Sample:
Lane 1: Mouse Kidney tissue lysates
Lane 2: Mouse Placenta tissue lysates
Lane 3: Human HepG2 cell lysates
Primary: Anti-Fibrinogen gamma chain (bs-6895R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kDa
Observed band size: 47 kDa
Lane 1: Mouse Kidney tissue lysates
Lane 2: Mouse Placenta tissue lysates
Lane 3: Human HepG2 cell lysates
Primary: Anti-Fibrinogen gamma chain (bs-6895R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kDa
Observed band size: 47 kDa
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文献和实验该产品被引用文献
[IF={{ 8.724 }}] {Qing Ma. et al. Durable endothelium-mimicking coating for surface bioengineering cardiovascular stents. Bioact Mater. 2021 Dec;6:4786} {Other} {}
[IF={{ 2.68 }}] {Li, Hongyan, et al. "Comparative analysis of the serum proteome for biomarker discovery to reveal hepatotoxicity induced by iron ion radiation in mice." Life Sciences 167 (2016): 57-66.} {WB} {="Mouse"}
[IF={{ 16.874 }}] {Bingcheng Yi. et al. Step-wise CAG@PLys@PDA-Cu2+ modification on micropatterned nanofibers for programmed endothelial healing. BIOACT MATER. 2022 Jul;:} {IHC} {Human}
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Fibrinogen gamma chain Rabbit pAb(bs-6895R)-50ul/100ul/200ul
￥1180 - 2800
