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IL-18R alpha Rabbit pAb(bs-261

5R)-50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-2615R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-2615R
    英文名称IL-18R alpha Rabbit pAb
    中文名称白细胞介素-18受体α链抗体
    英文别名interleukin-18 receptor alpha chain; Interleukin-18 receptor 1; IL-18R-1; IL-18R1; IL1 receptor-related protein; interleukin 1 receptor-like protein; IL-1Rrp; IL1R-rp; CD218 antigen-like family member A; CD218a; CDw218; CDw218a; CDw218a antigen; IL18RA; Il18ralpha; IL1RRP; interleukin 18 receptor 1.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse (Rat, Dog, Pig, Cow)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human IL-18R alpha
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量60 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Does not bind IL1A/interleukin-1 alpha or IL1B/interleukin-1 beta.
    亚细胞定位Membrane; Single-pass type I membrane protein.
    组织特异性Expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney. High level of expression in Hodgkin disease cell lines.
    相似性Belongs to the interleukin-1 receptor family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
    功能Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Lane 1: Mouse Blood cell lysates
    Lane 2: Mouse Lung tissue lysates
    Primary: Anti-IL-18R alpha (bs-2615R) at 1/500 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 60 kDa
    Observed band size: 70 kDa

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    图标文献和实验
    该产品被引用文献

    [IF={{ 7.4 }}] {Cailong Chen. et al. Lactoferrin ameliorated obesity-induced endothelial dysfunction by inhibiting the Tak1/IL-18/eNOS pathway between PVAT and vascular endothelium. FREE RADICAL BIO MED. 2023 Dec;:} {WB,IHC} {Mouse}

    [IF={{ 5.383 }}] {Ting Xiang. et al. Spinal CCK1 receptors contribute to somatic pain hypersensitivity induced by malocclusion via a reciprocal neuron-glial signaling cascade. J PAIN. 2022 Jun;:} {IHC} {Rat}

    [IF={{ 2.08 }}] {Zhang, Jihong, et al. "Interleukin 18 augments growth ability via NF-κB and p38/ATF2 pathways by targeting cylin B1, cyclin B2, cylin A2, and Bcl-2 in BRL-3A rat liver cells." Gene (2015).} {WB} {="Rat"}

    [IF={{ 1.585 }}] {Jiang et al. Detection of Atherosclerotic Plaques in the Rabbit Aorta Using Ultrasound Microbubbles Conjugated to Interleukin-18 Antibodies. (2017) Med.Sci.Moni. 23:5446-5454} {Other} {Rabbit}

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    文献支持
    IL-18R alpha Rabbit pAb(bs-2615R)-50ul/100ul/200ul
    ¥1180 - 2800