相关产品推荐更多 >

SHISA7 Rabbit pAb(bs-17466R)-50ul/100ul/200ul
¥1180
phospho-H2AX (Tyr143) Rabbit pAb(bs-5360R)-50ul/100ul/200ul
¥1180
Bcl-2 alpha Rabbit pAb, BF647 conjugated(bs-15533R-BF647)-100ul
¥2980
HMGB1 Rabbit pAb, Biotin conjugated(bs-0664R-Bio)-100ul
¥2980
KCNAB1/Kv beta 1 Rabbit pAb, Biotin conjugated(bs-8691R-Bio)-100ul
¥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围:
产品信息以Bioss网站为准
- 规格:
50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-2615R |
| 英文名称 | IL-18R alpha Rabbit pAb |
| 中文名称 | 白细胞介素-18受体α链抗体 |
| 英文别名 | interleukin-18 receptor alpha chain; Interleukin-18 receptor 1; IL-18R-1; IL-18R1; IL1 receptor-related protein; interleukin 1 receptor-like protein; IL-1Rrp; IL1R-rp; CD218 antigen-like family member A; CD218a; CDw218; CDw218a; CDw218a antigen; IL18RA; Il18ralpha; IL1RRP; interleukin 18 receptor 1. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse (Rat, Dog, Pig, Cow) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human IL-18R alpha |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 60 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Does not bind IL1A/interleukin-1 alpha or IL1B/interleukin-1 beta. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney. High level of expression in Hodgkin disease cell lines. |
| 相似性 | Belongs to the interleukin-1 receptor family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 TIR domain. |
| 功能 | Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Lane 1: Mouse Blood cell lysates
Lane 2: Mouse Lung tissue lysates
Primary: Anti-IL-18R alpha (bs-2615R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kDa
Observed band size: 70 kDa
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验[IF={{ 7.4 }}] {Cailong Chen. et al. Lactoferrin ameliorated obesity-induced endothelial dysfunction by inhibiting the Tak1/IL-18/eNOS pathway between PVAT and vascular endothelium. FREE RADICAL BIO MED. 2023 Dec;:} {WB,IHC} {Mouse}
[IF={{ 5.383 }}] {Ting Xiang. et al. Spinal CCK1 receptors contribute to somatic pain hypersensitivity induced by malocclusion via a reciprocal neuron-glial signaling cascade. J PAIN. 2022 Jun;:} {IHC} {Rat}
[IF={{ 2.08 }}] {Zhang, Jihong, et al. "Interleukin 18 augments growth ability via NF-κB and p38/ATF2 pathways by targeting cylin B1, cyclin B2, cylin A2, and Bcl-2 in BRL-3A rat liver cells." Gene (2015).} {WB} {="Rat"}
[IF={{ 1.585 }}] {Jiang et al. Detection of Atherosclerotic Plaques in the Rabbit Aorta Using Ultrasound Microbubbles Conjugated to Interleukin-18 Antibodies. (2017) Med.Sci.Moni. 23:5446-5454} {Other} {Rabbit}
that was an interspecific hybrid (H) between Mus musculus domesticus (D, paternal genome) and Mus spretus (S, maternal genome). The native chromatin was then immunoprecipitated with rabbit polyclonal antisera to acetylation at lysine 9 of H3 (H3K9Ac) and to dimethylation
F, Wu R, Morgan M, Thorburn A, Finely RL, Chen YQ. (2002). Mediation of the DCC apoptotic signal by DIP13 alpha. J. Biol. Chem. 277(29):26281-26285. Koepp DM, Schaefer LK, Ye X, Keyomarsi K, Chu C, Harper JW, and Elledge SJ. (2001
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
performance. StandardSDS-PAGE is an alternative to this system (18) . 2. Stock solutions of morpholinepropane sulphonic acid (MOPS)electrophoresis running buffer (20×), transfer buffer (20×),antioxidant solution (1,000×), SDS sample buffer (4×), andSeeBlue
技术资料暂无技术资料 索取技术资料





