BMP8b Rabbit pAb(bs-3670R)-50ul/100ul
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BMP8b Rabbit pAb(bs-3670R)-50u

l/100ul
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  • ¥1180 - 1980
  • Bioss已认证
  • bs-3670R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    产品编号bs-3670R
    英文名称BMP8b Rabbit pAb
    中文名称骨形态发生蛋白8抗体
    英文别名BMP8B_HUMAN; Bone morphogenetic protein 8B; BMP-8B; BMP-8; Osteogenic protein 2(OP-2); Osteogenic protein-2; OP2; OP 2; BMP8;
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse, Rat
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human BMP8B
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量45 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Homodimer; disulfide-linked.
    亚细胞定位Secreted.
    相似性Belongs to the TGF-beta family.
    功能Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

    BMP8b Rabbit pAb(bs-3670R)-50u
    P‌‌araformaldehyde-fixed, paraffin embedded (mouse pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (BMP8b) Polyclonal Antibody, Unconjugated (bs-3670R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    BMP8b Rabbit pAb(bs-3670R)-50u
    P‌‌araformaldehyde-fixed, paraffin embedded (rat pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (BMP8b) Polyclonal Antibody, Unconjugated (bs-3670R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    BMP8b Rabbit pAb(bs-3670R)-50u
    Sample:
    Lane 1: Human A549 cell lysates
    Lane 2: Human THP-1cell lysates
    Primary: Anti-BMP8b (bs-3670R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 45 kDa
    Observed band size: 45 kDa

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    图标文献和实验
    该产品被引用文献

    [IF={{ 4.491 }}] {Dong Liu. et al. Comprehensive landscape of TGFβ-related signature in osteosarcoma for predicting prognosis, immune characteristics, and therapeutic response. J BONE ONCOL. 2023 May;:100484} {WB} {Human}

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    文献支持
    BMP8b Rabbit pAb(bs-3670R)-50ul/100ul
    ¥1180 - 1980