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产品信息以Bioss网站为准
- 规格:
50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-3913R |
| 英文名称 | SLCO2B1 Rabbit pAb |
| 中文名称 | 可溶性载质转运蛋白2B1抗体 |
| 英文别名 | Moat 1; Moat1; Multispecific organic anion transporter 1; Multispecific organic anion transporter1; OATP 2B1; OATP B; OATP RP2; OATP2 B1; OATP2B1; OATPB; OATPRP 2; OATPRP2; Organic anion transporter B; Organic anion transporter polypeptide related protein 2; Organic anion transporter polypeptide related protein2; SLC 21A9; SLC2 1A9; SLC21 A9; SLC21A9; SLCO 2B1; SLCO2 B1; SO 2B1; SO2 B1; SO2B1; Solute carrier family 21(organic anion transporter), member 9; Solute carrier family 21 member 9; Solute carrier organic anion transporter family member 2B1; SO2B1_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SLCO2B1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 77 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Hormone biosynthesis Developmental Biology > Reproduction > Hormones Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Neuroscience > Neurology process > Neuroendocrinology > General neuroendocrinology Signal Transduction > Metabolism > Drug metabolism |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the organo anion transporter (TC 2.A.60) family. Contains 1 Kazal-like domain. |
| 功能 | Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SLCO2B1 (solute carrier organic anion transporter family member 2B1), or Organic anion transporter B (OATP-B) mediates sodium-independent transport of organic anions. Unlike other related proteins, SLCO2B1 is expressed in many tissues, including liver, placenta, brain, heart and intestine. SLCO2B1 plays a role in the uptake of steroids and a number of drugs such as statins. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Cerebrum (Mouse) Lysate at 40 ug
Cerebrum (Rat) Lysate at 40 ug
Primary: Anti- SLCO2B1 (bs-3913R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 77 kD
Observed band size: 87 kD
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文献和实验[IF={{ 3.84 }}] {Yamamoto, Kotaro, et al. "The neuroprotective effect of latanoprost acts via klotho‐mediated suppression of calpain activation after optic nerve transection." Journal of Neurochemistry (2016).} {IHC} {="Rat"}
[IF={{ 10.334 }}] {Wenlong Li. et al. Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs. PHARMACOL RES. 2023 Mar;:106724} {IHC} {Mouse}
[IF={{ 1.6 }}] {Shuangxi Sun. et al. Huatanmaitong tablet alleviate cerebral ischemic reperfusion injury with hyperlipidaemia in rats by regulating OATPs/VEGF axis. CELL MOL BIOL. 2023 Dec;69(13):} {WB} {Rat}
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