Sample:
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Jurkat(Human) Cell Lysate at 30 ug
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293T(Human) Cell Lysate at 30 ug
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A549(Human) Cell Lysate at 30 ug
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Primary: Anti- FOXR2 (bs-16176R) at 1/1000 dilution
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Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
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Predicted band size: 36 kD
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Observed band size: 36 kD
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- ￥1180 - 2800
- Bioss
- bs-16176R
- 2026年10月13日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-16176R |
| 英文名称 | FOXR2 Rabbit pAb |
| 中文名称 | 叉头蛋白R2抗体 |
| 英文别名 | Forkhead box protein N6; Forkhead box protein R2; FOXN6; FOXR2_HUMAN. |
| 产品应用 | WB=1:500-2000, ICC/IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Human |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human FOXR2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 36 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box > FOXN Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box > Other FOXes |
| 亚细胞定位 | Nuclear |
| 组织特异性 | Expressed in breast cancer cell lines and primary cancer. |
| 相似性 | Contains 1 fork-head DNA-binding domain. |
| 功能 | Forkhead-box (FOX) transcription factors are implicated in carcinogenesis through gene amplification, retroviral integration, or chromosomal translocation. Human FOXR2 mRNA was expressed in breast cancer cell line and primary breast cancer. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXR2 (Forkhead box protein R2), also known as FOXN6 (Forkhead box protein N6), is a 311 amino acid nuclear protein that belongs to the FOX family and contains one fork-head DNA-binding domain. Like other members of the FOX family, FOXR2 is not abundantly expressed in normal tissues but is found at very high levels in breast cancer and primary cancer cell lines and is thought to act as a transcription factor. Through chromosomal aberrations such as retroviral integration, gene amplification or translocation, FOXR2 may be involved the development of certain invasive carcinomas. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {ICC/IF} | {1:100-500} |
Hela cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (BrdU) polyclonal Antibody, Unconjugated (bsm-0917M) 1:50, 90 minutes at 37°C; followed by a conjugated Goat Anti-Mouse IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
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FOXR2 Rabbit pAb(bs-16176R)-50ul/100ul/200ul
￥1180 - 2800
