STAB2 | HARE Rabbit pAb(bs-12346R)-50ul/100ul/200ul产品图
文献支持

STAB2 | HARE Rabbit pAb(bs-123

46R)-50ul/100ul/200ul
收藏
  • ￥1180 - 2800
  • Bioss已认证
  • bs-12346R
  • 2026年10月13日
    avatar
    北京博奥森生物技术有限公司
    品牌商
    10 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品

    相关阅读

    香烟烟雾如何加速声带纤维化？CD44-透明质酸轴是关键通路Takara 秋促来袭，提取+反转录+定量套装仅 1200 元abinScience 体内级抗体 全年锁价 低至 ￥1200阿拉丁 22万+ 科研级产品现货速发，品质严控、科研无忧
    • 详细信息
    • 文献和实验
    • 技术资料
    • 规格：

      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-12346R
    英文名称Stabilin 2 Rabbit pAb
    中文名称清道夫受体STAB2抗体
    英文别名STAB 2; 190 kDa form stabilin-2; 190 kDa hyaluronan receptor for endocytosis; EGF-like; FAS1 EGF-like and X-link domain-containing adhesion molecule 2; Fasciclin; FEEL-2; FEEL2; FELL; FEX2; HARE; Hyaluronan receptor for endocytosis; laminin-type EGF-like and link domain-containing scavenger receptor 2; link domain-containing scavenger receptor 2; STAB-2; Stab2; STAB2_HUMAN.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat, Cow, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Stabilin 2
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量154/275 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cell Adhesion Molecules > Endothelial

    Stem Cells > Hematopoietic Progenitors > Surface Molecules

    亚细胞定位Cell membrane. Cytoplasm. Only a small amount appears to be present at the cell surface.
    组织特异性Highly expressed in sinusoidal endothelial cells of liver, spleen and lymph nodes. Also expressed in non SEC-cells such as HMDMs (monocyte-derivedmacrophages), HAMs (T-cell leukemia virus type 1-associated myelopathy), and several macrophage cell line.
    翻译后修饰Glycosylated.
    _x000D_ Proteolytically processed to yield a 190 kDa protein.
    相似性Contains 17 EGF-like domains.
    _x000D_ Contains 7 FAS1 domains.
    _x000D_ Contains 2 laminin EGF-like domains.
    _x000D_ Contains 1 Link domain.
    功能Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008].

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    Tissue/cell: mouse spleen tissue;4% P‌‌araformaldehyde-fixed and paraffin-embedded;
    _x000D_ Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
    _x000D_ Incubation: Anti-Stabilin 2 Polyclonal Antibody, Unconjugated(bs-12346R) 1:200, overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated(bs-0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C. DAPI(5ug/ml,blue,C-0033) was used to stain the cell nuclei
    _x000D_

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献

    [IF=10.392] Xiao Liang. et al. Phosphatidylserine released from apoptotic cells in tumor induces M2-like macrophage polarization through the PSR-STAT3-JMJD3 axis. 2022 Feb 22 FCM Mouse

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    STAB2 Rabbit pAb
    询价
    上海圻明生物科技有限公司
    2025年07月16日询价
    Rabbit Anti-Human STAB2 pAb
    询价
    卡梅德生物科技（天津）有限公司
    2026年06月04日询价
    STAB2 Rabbit Polyclonal Antibody
    ￥500
    北京百奥创新科技有限公司
    2025年05月19日询价
    STAB2 抗体-STAB2 Antibody
    ￥22
    艾美捷科技有限公司
    2025年07月16日询价
    Anti-STAB2 antibody produced in rabbit
    询价
    默克生命科学
    2026年04月14日询价
    文献支持
    STAB2 | HARE Rabbit pAb(bs-12346R)-50ul/100ul/200ul
    ￥1180 - 2800