Sample:
Lane 1: Human 293T cell lysates
Lane 2: Human A375 cell lysates
Lane 3: Human Raji cell lysates
Lane 4: Human HeLa cell lysates
Lane 5: Human HT-1080 cell lysates
Primary: Anti-OSMR (bs-5096R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 111 kDa
Observed band size: 110 kDa
- ￥1180 - 2800
- Bioss
- bs-5096R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-5096R |
| 英文名称 | OSMR Rabbit pAb |
| 中文名称 | 抑瘤素M受体抗体 |
| 英文别名 | Oncostatin M receptor; Oncostatin M specific receptor subunit beta; Interleukin-31 receptor subunit beta; IL-31 receptor subunit beta; IL-31R subunit beta; IL-31R-beta; IL-31RB; Oncostatin-M-specific receptor, beta; OSMRB; MGC140467; MGC150626; MGC150627; MGC75127. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Oncostatin-M receptor |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 111 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > STATs Immunology > Innate Immunity > Cytokines > IL6 Related Immunology > Innate Immunity > Cytokines > Interleukins Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus Signal Transduction > Signaling Pathway > Nuclear Signaling > STATs |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Expressed at relatively high levels in all neural cells as well as fibroblast, epithelial and a variety of tumor cell lines. |
| 相似性 | Belongs to the type I cytokine receptor family. Type 2 subfamily.
Contains 4 fibronectin type-III domains. |
| 功能 | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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OSMR Rabbit pAb(bs-5096R)-50ul/100ul/200ul
￥1180 - 2800
