ROBO1 | DUTT1 Rabbit pAb(bs-5794R)-50ul/100ul/200ul产品图
文献支持

ROBO1 | DUTT1 Rabbit pAb(bs-57

94R)-50ul/100ul/200ul
收藏
  • ￥1180 - 2800
  • Bioss已认证
  • bs-5794R
  • 2026年10月13日
    avatar
    北京博奥森生物技术有限公司
    品牌商
    10 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品

    相关阅读

    源叶生物 十万种现货试剂速发，品质稳、品类全，实验不再等！Takara 秋促来袭，提取+反转录+定量套装仅 1200 元abinScience 体内级抗体 全年锁价 低至 ￥1200阿拉丁 22万+ 科研级产品现货速发，品质严控、科研无忧
    • 详细信息
    • 文献和实验
    • 技术资料
    • 规格：

      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-5794R
    英文名称Robo Rabbit pAb
    中文名称轴突导向受体抗体
    英文别名Axon guidance receptor; Deleted in U twenty twenty; DUTT 1; DUTT1; FLJ21882; H Robo 1; H-Robo-1; hRobo 1; Robo 1; Robo1; ROBO1_HUMAN; Roundabout 1; Roundabout axon guidance receptor homolog 1; Roundabout homolog 1; Roundabout homolog1 precurser; Roundabout1; SAX 3; SAX3.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Rat (Human, Mouse)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Robo
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量181 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Invasion/microenvironment > Angiogenesis

    Neuroscience > Neurology process > Growth and Development > Axonal Guidance Proteins

    Neuroscience > Neurology process > Neurogenesis

    Neuroscience > Neurology process > Neuroregeneration > Neuroregeneration

    亚细胞定位Membrane.
    组织特异性Widely expressed, with exception of kidney.
    翻译后修饰Ubiquitinated. May be deubiquitinated by USP33.
    相似性Belongs to the immunoglobulin superfamily. ROBO family.
    _x000D_ Contains 3 fibronectin type-III domains.
    _x000D_ Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
    功能Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Specialized cells at the midline, which separates the left and right halves of the CNS, have a number of roles in directing growth cone behavior (1). In the vertebrate spinal cord, the insect ventral nerve cord and in C. elegans, midline cells produce guidance cues such as nectins and slit, which act as attractants and repellents, respectively (1). These cells may act as gatekeepers to prevent axons from crossing the midline and to induce a switch in growth cone responsiveness to guidance cues beyond the gateway (1). One such gatekeeper, Robo, is an axon guidance receptor that defines a novel subfamily of Ig superfamily proteins that are conserved from fruit flies to mammals (2,3). Robo acts as a receptor for the repellent Slit and functions in a cell-autonomous fashion (1-3). Non-crossing axons express high levels of Robo, whereas crossing axons express low levels of Robo before reaching the midline and high levels after they cross (1). Robo1 and Robo2 are two human homologs of the Drosophila protein Roundabout (2-4). Robo1 is also homologous to the C. elegans gene sax3, whereas Robo2 is homologous to the zebrafish gene astray (5,6).

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    Tissue/cell: rat brain tissue;4% P‌‌araformaldehyde-fixed and paraffin-embedded;
    _x000D_ Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
    _x000D_ Incubation: Anti-Robo Polyclonal Antibody, Unconjugated(bs-5794R) 1:200, overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated(bs-0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C. DAPI(5ug/ml,blue,C-0033) was used to stain the cell nuclei
    _x000D_

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献

    [IF=3.26] Liu, Xin-Qi, et al. "Regulation of neuroendocrine cells and neuron factors in the ovary by zinc oxide nanoparticles." Toxicology Letters (2016). IHC ="Chicken"

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    Robo1 / DUTT1 (mouse) Immunizing Peptide
    ￥3880
    上海联迈生物工程有限公司
    2026年06月04日询价
    Goat Anti-ROBO1 / DUTT1 (Internal) Antibody
    $495
    安诺伦（北京）生物科技有限公司
    2025年06月29日询价
    ROBO1 rabbit pAb
    ￥900
    上海贝博生物科技有限公司
    2026年03月12日询价
    Robo1 Rabbit pAb
    ￥1344
    广州市左克生物科技发展有限公司
    2026年04月20日询价
    ROBO1 Rabbit pAb(WB,FCM,ELISA)
    ￥1980
    上海圻明生物科技有限公司
    2025年07月07日询价
    文献支持
    ROBO1 | DUTT1 Rabbit pAb(bs-5794R)-50ul/100ul/200ul
    ￥1180 - 2800