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50ul/100ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 产品编号 | bs-2610R |
| 英文名称 | IL17RB Rabbit pAb |
| 中文名称 | 白介素-17B受体抗体 |
| 英文别名 | IL17B Receptor; Interleukin-17 receptor B; IL17RB; IL-17RB; CRL 4; CRL4; Cytokine receptor CRL4; EVI 27; EVI27; IL 17 receptor B; IL 17 receptor homolog 1; IL 17B receptor; IL 17RB; IL 17Rh1; IL17BR; IL17RH1; Interleukin 17 receptor B; Interleukin 17 receptor homolog 1; Interleukin 17 receptor homolog; Interleukin 17B receptor; ecotropic viral integration site 27; interleukin-17 receptor B precursor; MGC5245; I17RB_MOUSE. |
| 产品应用 | WB=1:500-2000, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human IL-17RB |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 54 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell cycle > Cell differentiation Cell Biology > Cell Cycle > Cell differentiation Immunology > Innate Immunity > Cytokines > Interleukins Immunology > Innate Immunity > Macrophage / Inflamm. |
| 亚基 | Interacts with DAZAP2. |
| 亚细胞定位 | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. |
| 组织特异性 | Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines. |
| 相似性 | Contains 1 SEFIR domain. |
| 功能 | Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {ELISA} | {1:5000-10000} |

Liver (Mouse) Lysate at 40 ug
Primary: Anti-IL17RB (bs-2610R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD

Lane 1: Rat Uterus tissue lysates
Lane 2: Mouse Uterus tissue lysates
Lane 3: Human A549 cell lysates
Lane 4: Human HepG2 cell lysates
Lane 5: Human HeLa cell lysates
Lane 6: Human MCF-7 cell lysates
Primary: Anti-IL17RB (bs-2610R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kDa
Observed band size: 50 kDa
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文献和实验[IF={{ 8.38 }}] {Gregory, Lisa G., et al. "IL-25 drives remodelling in allergic airways disease induced by house dust mite." Thorax 68.1 (2013): 82-90.} {IHC} {="Mouse"}
[IF={{ 3.636 }}] {Kawamura Teruhiko. et al. Identification of genes associated with endometrial cell ageing. Mol Hum Reprod. 2021 Feb;27(2):} {IHC} {Human}
[IF={{ 1.813 }}] {Xie Dong-ping. et al. Effect of Electroacupuncture at Zusanli (ST36) on Sepsis Induced by Cecal Ligation Puncture and Its Relevance to Spleen. Evid-Based Compl Alt. 2020;2020:1914031} {FCM} {Rat}
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Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
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