Sample:
Lane 1: Mouse Bone marrow Lysates
Lane 2: Mouse Spleen Lysates
Lane 3: Mouse Uterus Lysates
Lane 4: Mouse Testis Lysates
Lane 5: Mouse NIH/3T3 cell Lysates
Lane 6: Rat Bone marrow Lysates
Lane 7: Rat Spleen Lysates
Lane 8: Rat Uterus Lysates
Lane 9: Rat Testis Lysates
Lane 10: Human Jurkat cell Lysates
Lane 11: Human A549 cell Lysates
Lane 12: Human HL-60 cell Lysates
Lane 13: Human MCF-7 cell Lysates
Lane 14: Human HepG2 cell Lysates
Primary: Anti-MMP8 (bs-1913R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38kDa
Observed band size: 60kDa
- ￥1180 - 1980
- Bioss
- bs-1913R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 产品编号 | bs-1913R |
| 英文名称 | MMP8 Rabbit pAb |
| 中文名称 | 基质金属蛋白酶-8/胶原酶2抗体 |
| 英文别名 | Matrilysin/matrix metalloproteinases-8; CLG 1; CLG1; Collagenase II; Collagenase 2; Collagenase neutrophil; HNC; Matrix metalloprotease 8; MMP8; MMP 8; MMP-8; Neutrophil collagenase; PMNL CL; PMNL collagenase; PMNLCL; neutrophil collagenase preproprotein; MMP8_HUMAN; Neutrophil collagenase; Matrix metalloproteinase-8; PMNL-CL. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MMP8 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 38 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Invasion/microenvironment > ECM > Extracellular matrix > MMPs Cancer > Tumor biomarkers > Enzymes > MMPs Cardiovascular > Angiogenesis > Adhesion / ECM > Matrix Metalloproteinases > MMP Cardiovascular > Atherosclerosis > Vascular Inflammation > Leukocyte recruitment Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Metalloprotease > MMPs Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Atherosclerotic proteins ELISA kits Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Tumor biomarkers ELISA kits Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > MMP |
| 亚细胞定位 | Cytoplasmic granule. Secreted, extracellular space, extracellular matrix (Probable). Note=Stored in intracellular granules. |
| 组织特异性 | Neutrophils. |
| 相似性 | Belongs to the peptidase M10A family. Contains 4 hemopexin-like domains. |
| 功能 | Can degrade fibrillar type I, II, and III collagens. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 5.246 }}] {Yin Zhuang. et al. Exosomes Secreted by Nucleus Pulposus Stem Cells Derived From Degenerative Intervertebral Disc Exacerbate Annulus Fibrosus Cell Degradation via Let-7b-5p. Front Mol Biosci. 2021; 8: 766115} {WB} {Human}
[IF={{ 3.27 }}] {Oralova, V., et al. "Osteogenic Potential of the Transcription Factor c-MYB." Calcified Tissue International: 1-12.} {WB} {="Mouse"}
[IF={{ 3.04 }}] {Sîrbulescu, Ruxandra F., et al. "Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions." Wound Repair and Regeneration (2017).} {IHC} {="Mouse"}
[IF={{ 2.35 }}] {Zhang, Chao-ying, et al. "Hydrogen sulfide suppresses the expression of MMP-8, MMP-13, and TIMP-1 in left ventricles of rats with cardiac volume overload." Acta Pharmacologica Sinica (2013).} {Other} {="Rat"}
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MMP8 Rabbit pAb(bs-1913R)-50ul/100ul
￥1180 - 1980
