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THBS1 Rabbit pAb(bs-2715R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-2715R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-2715R
    英文名称THBS1 Rabbit pAb
    中文名称血小板反应蛋白抗体
    英文别名THBS 1; THBS-1; THBS; Thrombospondin 1; Thrombospondin1; Thrombospondin-1; Tsp 1; TSP-1; TSP; Tsp1.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Zebrafish)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human TSP-1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量129 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Blood > Coagulation > Regulatory

    Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Regulation

    相似性Belongs to the thrombospondin family.
    Contains 3 EGF-like domains.
    Contains 1 TSP C-terminal (TSPC) domain.
    Contains 1 TSP N-terminal (TSPN) domain.
    Contains 3 TSP type-1 domains.
    Contains 8 TSP type-3 repeats.
    Contains 1 VWFC domain.
    功能Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq].

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    P‌‌araformaldehyde-fixed, paraffin embedded (human myocardial tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (THBS1) Polyclonal Antibody, Unconjugated (bs-2715R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    产品细节图片2
    Sample:
    293T(Human) Cell Lysate at 30 ug
    Primary: Anti-THBS1 (bs-2715R) at 1/2000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 129 kD
    Observed band size: 129 kD

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    图标文献和实验
    该产品被引用文献

    [IF={{ 7.7 }}] {Yufang Niu. et al. The long noncoding RNA lncMPD2 inhibits myogenesis by targeting the miR-34a-5p/THBS1 axis. INT J BIOL MACROMOL. 2024 Aug;275:133688} {WB} {Chicken}

    [IF={{ 7.2 }}] {Zheng Zeng. et al. Enterolactone and trabectedin suppress epithelial ovarian cancer synergistically via upregulating THBS1. PHYTOTHER RES. 2023 Jul;:} {WB} {Mouse}

    [IF={{ 5.6 }}] {Maggie Lutz. et al. Therapeutic Targeting of the GSK3β-CUGBP1 Pathway in Myotonic Dystrophy. INT J MOL SCI. 2023 Jan;24(13):10650} {WB} {Mouse}

    [IF={{ 4.932 }}] {Qifeng Deng. et al. Cordycepin enhances anti-tumor immunity in colon cancer by inhibiting phagocytosis immune checkpoint CD47 expression. Int Immunopharmacol. 2022 Jun;107:108695} {WB} {Mouse}

    [IF={{ 4.803 }}] {Duan F et al. THBS1 regulates trophoblast fusion through a CD36-dependent inhibition of cAMP, and its upregulation participates in preeclampsia. Genes & Diseases, (2020), S2352304220300726–.} {WB} {Human}

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    文献支持
    THBS1 Rabbit pAb(bs-2715R)-50ul/100ul/200ul
    ¥1180 - 2800