Sample:
Lane1：Islet A lysates at 20ug;
Lane2：Islet B lysates at 20ug;
Primary: Anti-Insulin (bs-0862R) at 1:300 dilution;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution;
Predicted band size:5.8 kD
Observed band size:5.8 kD
- ￥1180 - 2800
- Bioss
- bs-0862R
- 2025年10月24日
- 产品信息以Bioss网站为准
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产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-0862R |
| 英文名称 | Insulin Rabbit pAb |
| 中文名称 | 胰岛素抗体 |
| 英文别名 | ILPR; INS; Insulin A chain; Insulin B chain; Insulin A chain; Insulin precursor; IRDN; Proinsulin; Proinsulin precursor; IDDM2; INS_HUMAN; MODY10. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Pig (Human, Mouse, Rat) |
| 抗体来源 | Rabbit |
| 免疫原 | porcine pancreas ，full length |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 5.77754 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Atherosclerosis > Diabetes associated Metabolism > Types of disease > Diabetes Metabolism > Types of disease > Heart disease Metabolism > Types of disease > Obesity Neuroscience > Neurology process > Metabolism Signal Transduction > Growth Factors/Hormones > Insulin / Insulin-like |
| 亚基 | Heterodimer of a B chain and an A chain linked by two disulfide bonds. |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the insulin family. |
| 功能 | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 6.1 }}] {Paritosh Ghosh. et al. Pancreatic β cell derived extracellular vesicles containing surface preproinsulin are involved in glucose stimulated insulin secretion. LIFE SCI. 2024 Mar;340:122460} {WB} {Human}
[IF={{ 5.705 }}] {Sun HD et al. Electrochemical sandwich immunoassay for insulin detection based on the use of gold nanoparticle-modified MoS 2 nanosheets and the hybridization chain reaction. Microchimica Acta,2018 186(1).} {Other} {}
[IF={{ 5.6 }}] {Yuyao Zhang. et al. Enhanced Electrochemiluminescence from Ruthenium-Tagged Immune Complex at Flexible Chains for Sensitive Analysis of Glutamate Decarboxylase Antibody. BIOSENSORS-BASEL. 2025 Jan;15(1):47} {} {Human}
[IF={{ 4.927 }}] {Hany Ezzat Khalil. et al. Mechanistic Insights into the Ameliorative Effect of Cichoriin on Diabetic Rats—Assisted with an In Silico Approach. MOLECULES. 2022 Jan;27(21):7192} {IHC} {Rat}
[IF={{ 4.556 }}] {Hsiao-Pei Tsai. et al. Risperidone Exacerbates Glucose Intolerance, Nonalcoholic Fatty Liver Disease, and Renal Impairment in Obese Mice. Int J Mol Sci. 2021 Jan;22(1):409} {IHC} {Mouse}
相关实验
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
Primary Kidney Proximal Tubule Cells
Primary rabbit kidney epithelial cell cultures can be obtained that express renal proximal tubule functions. Toward these ends, renal proximal tubules are purified from the rabbit kidney by the method of Brendel and Meezan. To summarize
A Simple and Reliable Assay of Proteoglycan Synthesis by Cultured Chondrocytes
, and its radioactivity is measured. Counts are proportional to the amount of neosynthesized proteoglycans. In a representative experiment using rabbit chondrocytes, total proteoglycan synthesis (SP plus CAP) was increased 3.5-fold after the addition of 1.34 nM insulin
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Insulin Rabbit pAb(bs-0862R)-50ul/100ul/200ul
￥1180 - 2800
