Cytokeratin 8(Ready to use) Mouse mAb(BH0008)-3ml/6ml

Cytokeratin 8(Ready to use) Mo

use mAb(BH0008)-3ml/6ml
收藏
  • ￥360 - 640
  • Bioss已认证
  • BH0008
  • 2025年10月24日
  • 产品信息以Bioss网站为准
avatar
北京博奥森生物技术有限公司
品牌商
9 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 技术资料
    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      3ml/6ml

    规格：3ml产品价格：￥360.0
    规格：6ml产品价格：￥640.0
    产品编号BH0008
    英文名称Cytokeratin 8(Ready to use) Mouse mAb
    中文名称人细胞角蛋白8单克隆抗体（即用型）
    英文别名card2; Cardiac autoantigen 2 120kD; CK 8; CK8; CK-8; ck8; Cyk 8; cyk8; CYKER; Cytokeratin endo A; Cytokeratin-8; Cytokeratin8; DreK8; EndoA; k0; CYK8; k2c8; K2C8_HUMAN; k8; Keratin 8; Keratin type ii cytoskeletal 8; Keratin, type II cytoskeletal 8; Keratin-8; Keratin8; KO; Krt 2.8; Krt 8; krt8; KRT-8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8.
    产品应用IHC-P, IHC-F, IF

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 (Human)
    抗体来源Mouse
    免疫原KLH conjugated synthetic peptide derived from human Cytokeratin 8
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Monoclonal
    理论分子量53 kDa
    储存液0.01M PBS (pH7.4) with 1% BSA and 0.02% Proclin300.
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Intermediate Filaments > Class I > Cytokeratins

    亚基Heterotetramer of two type I and two type II keratins. KRT8 associates with KRT18. Associates with KRT20. Interacts with HCV core protein and PNN. When associated with KRT19, interacts with DMD. Interacts with TCHP. Interacts with APEX1.
    亚细胞定位Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
    组织特异性Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.
    翻译后修饰Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization.
    O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation.
    O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.
    相似性Belongs to the intermediate filament family.
    功能Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
    保存条件Store at 2-8℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].

     

    应用推荐稀释比例

     

    Cytokeratin 8(Ready to use) Mo
    P‌‌araformaldehyde-fixed, paraffin embedded (Ovarian tumor(cysticadenocarcinoma)); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Cytokeratin 8(Ready to use)) Monoclonal Antibody, Unconjugated (BH0008) overnight at 4°C, followed by operating according to SP Kit(Mouse)(sp-0024) instructionsand DAB staining.
    Cytokeratin 8(Ready to use) Mo
    P‌‌araformaldehyde-fixed, paraffin embedded (Human colon adenocarcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Cytokeratin 8(Ready to use)) Monoclonal Antibody, Unconjugated (BH0008) overnight at 4°C, followed by operating according to SP Kit(Mouse)(sp-0024) instructionsand DAB staining.
    Cytokeratin 8(Ready to use) Mo
    P‌‌araformaldehyde-fixed, paraffin embedded (Human Paratracheal lymph nodes ); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Cytokeratin 8(Ready to use)) Monoclonal Antibody, Unconjugated (BH0008) overnight at 4°C, followed by operating according to SP Kit(Mouse)(sp-0024) instructionsand DAB staining.

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    Cytokeratin 6 (ABT052) Mouse mAb (Ready to Use)
    询价
    ImmunoWay Biotechnology Company
    2025年07月15日询价
    pan Cytokeratin antibody (ready-to-use)
    ￥5000
    GeneTex
    2025年07月15日询价
    pan Cytokeratin antibody (ready-to-use)
    ￥5000
    深圳欣博盛生物科技有限公司
    2025年07月11日询价
    basic Cytokeratin Antibody (ready-to-use)
    ￥415
    上海联迈生物工程有限公司
    2025年07月07日询价
    Cytokeratin 19 antibody (ready-to-use)
    ￥2000
    上海钰博生物科技有限公司
    2025年06月12日询价
    Cytokeratin 8(Ready to use) Mouse mAb(BH0008)-3ml/6ml
    ￥360 - 640