- ￥680 - 5600
- Bioss
- bsm-33040M
- 2025年10月16日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/500ul/200ug
| 规格： | 50ul | 产品价格： | ￥680.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥980.0 |
| 规格： | 500ul | 产品价格： | ￥4000.0 |
| 规格： | 200ug | 产品价格： | ￥5600.0 |
| 产品编号 | bsm-33040M |
| 英文名称 | lamin B1 Mouse mAb, Nuclear Loading Control |
| 中文名称 | 核纤层蛋白B（核内参）单克隆抗体 |
| 英文别名 | LMNB1_HUMAN; Lamin-B1; LMNB1; LMN2; LMNB; LMN; ADLD; MCPH26; |
| 产品应用 | WB=1:1000-5000, IHC-P=1:200-1000, IHC-F=1:200-1000, IF=1:200-1000 Not yet tested in other applications. |
| 交叉反应 | Human, Rat |
| 抗体来源 | Mouse |
| 免疫原 | Recombinant human Lamin B Protein |
| 亚型 | IgG1 |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 理论分子量 | 64 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell Death > Apoptosis > Nucleus > Lamins Cell Biology > Apoptosis > Nucleus > Lamins Isotype/Loading Controls > Loading Controls > Lamin B1 - Nuclear Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Intermediate Filaments > Class V > Lamins Tags & Cell Markers > Subcellular Markers > Nucleus > Nuclear Envelope |
| 亚基 | Homodimer. Interacts with lamin-associated polypeptides IA, IB and 2. |
| 亚细胞定位 | Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side. |
| 翻译后修饰 | B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. |
| 相似性 | Belongs to the intermediate filament family. |
| 功能 | Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验[IF={{ 5.195 }}] {Yanqiu Sun. et al. Xinfeng capsule inhibits inflammation and oxidative stress in rheumatoid arthritis by up-regulating LINC00638 and activating Nrf2/HO-1 pathway. J ETHNOPHARMACOL. 2023 Jan;301:115839} {WB} {Human}
Analysis of Nuclear and Cytoplasmic Degradation of p53 in Cells after Stress
after a stress stimulus. The fractions are then analyzed by immunoblotting in a time-dependent fashion. Vimentin and lamin A proteins are used to monitor the purity of the cytosolic and nuclear fractions, respectively, and to control for equal loading.
Mechanical Properties of Interphase Nuclei Probed by Cellular Strain Application
The mechanical properties of the interphase nucleus have important implications for cellular function and can reflect changes in nuclear envelope structure and/or chromatin organization. Mutations in the nuclear envelope proteins lamin
aactggacttccagaagaaca (90% reduction; 2) Human HeLa lamin B1 (1) NM_005573 672-694 aacgcgcttggtagaggtgga Human HeLa lamin B2 (1) M94362 1457-1479 aagaggaggaggaagccgagt Human HeLa LAP2 (1) NM_003276 37-59 aaagacaagttgaagagtgag Human HeLa Mad1 (41) AF083811
技术资料暂无技术资料 索取技术资料
