CD68 Mouse Monoclonal Antibody

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The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.

Product Name:CD68 Mouse Monoclonal Antibody

Clone Number: 7F4

Isotype: IgG1

Storage Buffer :PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol

Storage instructions:-20°C. Do not aliquot the antibody

Recommended dilutions: IHC: 1:200

Optimal dilutions should be determined by the end user.

Specificity:The CD68 antibody detects endogenous CD68 proteins.

Molecular Weight:37KD

Form: Liquid

Reactivity:H, M, R

IHC staining of human tonsil tissue CD68 mouse mAb(7F4) diluted at 1:200.