- ￥1919 - 11950
- TargetMol
- USA
- T2705
- 2025年07月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -2721℃ for several months.
- 英文名：
Mutant EGFR inhibitor
- 库存：
详询
- 供应商：
详询
- CAS号：
1421373-62-7
- 规格：
2mg/5mg/10mg/25mg/50mg/1ml/10mM
| 规格： | 2mg | 产品价格： | ￥1919.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥2900.0 |
| 规格： | 10mg | 产品价格： | ￥4300.0 |
| 规格： | 25mg | 产品价格： | ￥7794.0 |
| 规格： | 50mg | 产品价格： | ￥11950.0 |
| 规格： | 1ml/10mM | 产品价格： | ￥3232.0 |
ID：T2705
PURITY：0.977
Formula：C27H30ClN7O2
MolWt：520.03
Appearance：黄色粉末
Solubility：G410 mM in DMSO
Bioactivity：Mutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor(L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant).
Status：Undetermined activity
Pathways：Tyrosine Kinase/Adaptors
Target：EGFR inhibitor
Receptor：Mutated EGFR
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文献和实验EGFR and Tumor Suppressor Function in Brain Cancer Development
interventions. Using cutting edge Cre/Lox technologies, we created compound conditional transgenic strains based on a Cre-induced expression of mutant EGFRvIII with the concomitant loss of the Cdkn2a and PTEN tumor suppressor genes. The introduction
Methods for Studying the Interaction of Barnase with Its Inhibitor Barstar
inside the cell. The three-dimentional structures of barnase and barstar are known both from X-ray crystallography and NMR spectroscopy (1 –4 ). The crystal structure of the complex of barnase with the barstar (C40A/C82A) double mutant has been solved by Guillet
Detecting Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma
in the majority of treated patients and confer overall survival benefits, acquired drug resistance is a formidable obstacle to long-term management of the disease. Several aberrant events including RTK upregulation, NRAS mutation, mutant BRAF amplification
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