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Quizartinib (AC220)

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  • ¥747 - 5152
  • TargetMol
  • USA
  • T2066
  • 2025年07月07日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      -20°C

    • 保质期

      For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -2098℃ for several months.

    • 英文名

      Quizartinib (AC220)

    • 库存

      详询

    • 供应商

      详询

    • CAS号

      950769-58-1

    • 规格

      2mg/5mg/10mg/25mg/50mg/1ml/10mM

    规格:2mg产品价格:¥747.0
    规格:5mg产品价格:¥1010.0
    规格:10mg产品价格:¥1717.0
    规格:25mg产品价格:¥2742.0
    规格:50mg产品价格:¥5152.0
    规格:1ml/10mM产品价格:¥830.0

    ID:T2066

    PURITY:0.98

    Formula:C23H28ClN3O4

    MolWt:445.94

    Appearance:黄色粉末

    Solubility:G4DMSO > 10 mM

    Bioactivity:Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Phase 3.

    Status:

    Pathways:Tyrosine Kinase/Adaptors

    Target:FLT3 inhibitor

    Receptor:FLT3

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    图标文献和实验
    相关实验
    • Isolation of Sequences Flanking Ac Insertion Sites by Ac Casting

      Localizing Ac insertions is a fundamental task in studying Ac -induced mutation and chromosomal rearrangements involving Ac elements. Researchers may sometimes be faced with the situation in which the sequence flanking one side of an Ac /Ds

    • AC-Electrokinetic Applications in a Biological Setting

      Dielectrophoresis is a phenomenon which can be exploited to provide significant quantitative electrophysiological data in a range of biochemical setting, from oncology to drug discovery. This chapter seeks to elucidate those applications

    • Transposon Tagging with AC/Ds in Arabidopsis

      (2 ‐5 ). In Arabidopsis, Actzvator/Dissoclation (AC/ Ds) have been used to isolate recessive loss-of-function mutations (6 —8 ), dommant gain of function mutations (9 ) and to isolate genes based on then patterns of expression (10 ,11 ).

    图标技术资料

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