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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C
- 保质期:
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -2098℃ for several months.
- 英文名:
Quizartinib (AC220)
- 库存:
详询
- 供应商:
详询
- CAS号:
950769-58-1
- 规格:
2mg/5mg/10mg/25mg/50mg/1ml/10mM
| 规格: | 2mg | 产品价格: | ¥747.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥1010.0 |
| 规格: | 10mg | 产品价格: | ¥1717.0 |
| 规格: | 25mg | 产品价格: | ¥2742.0 |
| 规格: | 50mg | 产品价格: | ¥5152.0 |
| 规格: | 1ml/10mM | 产品价格: | ¥830.0 |
ID:T2066
PURITY:0.98
Formula:C23H28ClN3O4
MolWt:445.94
Appearance:黄色粉末
Solubility:G4DMSO > 10 mM
Bioactivity:Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Phase 3.
Status:
Pathways:Tyrosine Kinase/Adaptors
Target:FLT3 inhibitor
Receptor:FLT3
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文献和实验Isolation of Sequences Flanking Ac Insertion Sites by Ac Casting
Localizing Ac insertions is a fundamental task in studying Ac -induced mutation and chromosomal rearrangements involving Ac elements. Researchers may sometimes be faced with the situation in which the sequence flanking one side of an Ac /Ds
AC-Electrokinetic Applications in a Biological Setting
Dielectrophoresis is a phenomenon which can be exploited to provide significant quantitative electrophysiological data in a range of biochemical setting, from oncology to drug discovery. This chapter seeks to elucidate those applications
Transposon Tagging with AC/Ds in Arabidopsis
(2 ‐5 ). In Arabidopsis, Actzvator/Dissoclation (AC/ Ds) have been used to isolate recessive loss-of-function mutations (6 —8 ), dommant gain of function mutations (9 ) and to isolate genes based on then patterns of expression (10 ,11 ).
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