- ￥448 - 2400
- TargetMol
- USA
- T1776
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -1807℃ for several months.
- 英文名：
Plerixafor
- 库存：
详询
- 供应商：
详询
- CAS号：
110078-46-1
- 规格：
5mg/10mg/25mg/50mg/1ml/10mM
| 规格： | 5mg | 产品价格： | ￥450.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥653.0 |
| 规格： | 25mg | 产品价格： | ￥1313.0 |
| 规格： | 50mg | 产品价格： | ￥2400.0 |
| 规格： | 1ml/10mM | 产品价格： | ￥448.0 |
ID：T1776
PURITY：0.98
Formula：C28H54N8
MolWt：502.78
Appearance：白色晶体粉末
Solubility：G4Soluble in ethanol
Bioactivity：Plerixafor is a bicyclam with hematopoietic stem cell-mobilizing activity. Plerixafor blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow and HSC movement into the peripheral circulation.
Status：
Pathways：GPCR/G Protein
Target：CXCR antagonist
Receptor：CXCR
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文献和实验Hematopoietic Stem Cell Mobilization: A Clinical Protocol
following chemotherapy and/or growth factor-mediated mobilization. Most mobilization regimens consist of chemotherapy followed by one or more growth factors such as G-CSF, GM-CSF, or plerixafor. Occasionally a subset of patients will prove unable to mobilize
Hematopoietic Progenitor Cell Collection
Hematopoietic progenitor cells can be mobilized from the bone marrow microenvironment into the peripheral blood following treatment of patients with myeloid cytokines (GCSF, GMCSF, IL3), a CXCR4 antagonist (Plerixafor) and/or following
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