- ￥298 - 779.50
- TargetMol
- USA
- T1675
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -1715℃ for several months.
- 英文名：
Adefovir dipivoxil
- 库存：
详询
- 供应商：
详询
- CAS号：
142340-99-6
- 规格：
10mg/50mg/100mg/1ml/10mM
| 规格： | 10mg | 产品价格： | ￥298.0 |
|---|---|---|---|
| 规格： | 50mg | 产品价格： | ￥472.75 |
| 规格： | 100mg | 产品价格： | ￥779.5 |
| 规格： | 1ml/10mM | 产品价格： | ￥485.0 |
ID：T1675
PURITY：0.98
Formula：C20H32N5O8P
MolWt：501.47
Appearance：白色粉末
Solubility：G4Water：19 mg/mL at pH 2.0
Bioactivity：Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.
Status：
Pathways：Microbiology & Virology
Target：Antiviral; Reverse Transcriptase Inhibitor
Receptor：Reverse Transcriptase Inhibitor;Protein P;Reverse Transcriptase
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文献和实验作者: Lo YMD, Chan LYS, Lo KW, et al. 来源出版物: CANCER RESEARCH 卷: 59 期: 6 页: 1188-1191 出版年: MAR 15 1999 被引频次: 231 2. 标题: Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy 作者
Designing Clinical Development Programs for Anti-Hepatitis B Virus Drugs
hepatitis B—interferon, lamivudine, and adefovir—allow clinical management of some patients but are associated with frequent nonresponse (interferon), frequent viral resistance (lamivudine), or potential safety issues (adefovir), so additional treatment
Genotyping Anti-Hepatitis B Virus Drug Resistance
, such as lamivudine and adefovir (1 ). Currently, the only therapies approved in the United States for treatment of chronic HBV infection are IFN-α and lamivudine. However, a number of nucleoside and nucleotide analogs are in development, and it is likely
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