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- 文献和实验
- 技术资料
- 保存条件:
-20°C
- 保质期:
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -1562℃ for several months.
- 英文名:
Teniposide
- 库存:
详询
- 供应商:
详询
- CAS号:
29767-20-2
- 规格:
2mg/10mg/50mg/100mg/1ml/10mM
| 规格: | 2mg | 产品价格: | ¥338.5 |
|---|---|---|---|
| 规格: | 10mg | 产品价格: | ¥1087.0 |
| 规格: | 50mg | 产品价格: | ¥3088.0 |
| 规格: | 100mg | 产品价格: | ¥4658.0 |
| 规格: | 1ml/10mM | 产品价格: | ¥685.0 |
ID:T1523
PURITY:99%+
Formula:C32H32O13S
MolWt:656.66
Appearance:白色粉末
Solubility:G4DMSO 40mg/mL; Water <1 mg/mL; Ethanol <1 mg/mL
Bioactivity:A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead to cell death. Teniposide acts primarily in the G2 and S phases of the cycle.
Status:USAN, INN, BAN
Pathways:DNA Damage/DNA Repair
Target:Topoisomerase inhibitor
Receptor:Topoisomerase II
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文献和实验The Role of Biotechnology in the Production of the Anticancer Compound Podophyllotox
Podophyllotoxin is a plant-derived compound found in Podophyllum sp. that is used to produce semi-synthetic anticancer pharmaceuticals such as etoposide, teniposide, and etoposide phosphate. This chapter describes the role
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