- ￥218 - 1087
- TargetMol
- USA
- T1398
- 2025年07月11日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -1438℃ for several months.
- 英文名：
Cialis
- 库存：
详询
- 供应商：
详询
- CAS号：
171596-29-5
- 规格：
2mg/10mg/50mg/100mg/1ml/10mM
| 规格： | 2mg | 产品价格： | ￥328.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥458.0 |
| 规格： | 50mg | 产品价格： | ￥718.0 |
| 规格： | 100mg | 产品价格： | ￥1087.0 |
| 规格： | 1ml/10mM | 产品价格： | ￥218.0 |
ID：T1398
PURITY：0.98
Formula：C22H19N3O4
MolWt：389.4
Appearance：白色粉末
Solubility：G4Soluble in water
Bioactivity：Tadalafil is an orally adminstered drug used to treat male erectile dysfunction (impotence). It is marketed worldwide under the brand name Cialis. It is a phosphodiesterase 5 (PDE5) inhibitor. Tadalafil's distinguishing pharmacologic feature is its longer half-life (17.5 hours) compared with Viagra and Levitra (4-5 hours). This longer half-life results in a longer duration of action and is, in part, responsible for the Cialis nickname of the "weekend pill." This longer half-life also is the basis of current investigation for tadalafil's use in pulmonary arterial hypertension as a once-daily therapy.
Status：USAN, INN
Pathways：Metabolism
Target：PDE inhibitor
Receptor：PDE
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- 作者
- 内容
- 询问日期
文献和实验Radiolabeled Ligand Binding to the Catalytic or Allosteric Sites of PDE5 and PDE11
-monophosphate (cGMP) at both its catalytic site and its allosteric sites, has generated particular interest because it is potently and specifically inhibited by three drugs: sildenafil (Viagra™, Pfizer), tadalafil (Cialis™, Lilly-ICOS), and vardenafil (Levitra™
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