- ￥157 - 473
- TargetMol
- USA
- T1065
- 2025年07月10日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
2-8°C
- 保质期：
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -1104℃ for several months.
- 英文名：
Baclofen
- 库存：
详询
- 供应商：
详询
- CAS号：
1134-47-0
- 规格：
10mg/50mg/100mg/1ml/10mM
| 规格： | 10mg | 产品价格： | ￥157.0 |
|---|---|---|---|
| 规格： | 50mg | 产品价格： | ￥277.0 |
| 规格： | 100mg | 产品价格： | ￥473.0 |
| 规格： | 1ml/10mM | 产品价格： | ￥218.0 |
ID：T1065
PURITY：0.99
Formula：C10H12ClNO2
MolWt：213.66
Appearance：白色粉末
Solubility：G4Soluble in water
Bioactivity：A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.
Status：USP, INN, BAN, JAN
Pathways：Neuroscience
Target：GABAR agonist
Receptor：GABA-B Receptor
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文献和实验[3H]-GABA Binding to GABAA and GABAB Sites on Rat Brain Crude Synaptic Membranes
of antagonism by bicuculline and insensitivity to the GABA-analog baclofen, whereas GABAB receptors are stimulated by baclofen and are insensitive to bicuculline; GABAC receptors are insensitive to both (1 ).
Characterization of GABA Receptors
or ion?channel binding sites. Curr. Protoc. Pharmacol . 63:1.7.1?1.7.20. © 2013 by John Wiley & Sons, Inc. Keywords: gamma amino butyric acid; neurotransmitter; muscimol; baclofen; CNS; ligand binding
佚名 Pathophysiologic concepts Arousal
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