For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -509℃ for several months.
英文名:
Zileuton
库存:
详询
供应商:
详询
CAS号:
111406-87-2
规格:
2mg/10mg/20mg/50mg/100mg/1ml/10mM
规格:
2mg
产品价格:
¥108.0
规格:
10mg
产品价格:
¥348.0
规格:
20mg
产品价格:
¥638.5
规格:
50mg
产品价格:
¥1188.0
规格:
100mg
产品价格:
¥1998.0
规格:
1ml/10mM
产品价格:
¥358.0
ID:T0477
PURITY:0.99
Formula:C11H12N2O2S
MolWt:236.29
Appearance:白色粉末
Solubility:G4Soluble in water
Bioactivity:Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and eosinophil migration, neutrophil and monocyte aggregation, leukocyte adhesion, increased capillary permeability, and smooth muscle contraction. These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients. Zileuton relieves such symptoms through its selective inhibition of 5-lipoxygenase, the enzyme that catalyzes the formation of leukotrienes from arachidonic acid. Specifically, it inhibits leukotriene LTB4, LTC4, LTD4, and LTE4 formation. Both the R(+) and S(-) enantiomers are pharmacologically active as 5-lipoxygenase inhibitors in in vitro systems. The immediate release tablet of Zileuton has been withdrawn from the US market.